Results 61 to 70 of about 4,684,020 (381)
Management of risks at the insurance companies and solvency II [PDF]
Megatrend Revija, 2016 If we assume that the key determination of each insurance company is in increasing the competitiveness of the offer of insurance services, growth in the market share and making a profit, the question is how and by what methods these pretty often opposite
Sokić Miro +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The problem of legislative regulation of outsourcing in the insurance industry
Ученые записки Российской академии предпринимательства, 2021 The article is analyzed the Russian and foreign experience of legal regulations of outsourcing in the insurance industry, as well as proposed of recommendations for improvement legislative regulation.
M. A. Fedorov
doaj
Bond portfolio management under Solvency II regulation
European Journal of Finance, 2020 We develop a novel approach to the bond portfolio optimization for insurance companies that are subject to the new Solvency II regulation. The regulatory efficient portfolios are determined using the Non-dominated Sorting Genetic Algorithm II (NSGA-II ...
Mikica Drenovak +3 more
semanticscholar +1 more source
Comparative analysis of interest rate term structures in the Solvency II environment
, 2021 PurposeSolvency-II is the current regulatory framework of insurance companies in the European Union. Under this standard, European Insurance and Occupational Pension Authority (EIOPA), as a regulatory board, has established that the Smith–Wilson (SW ...
Mariano González Sánchez +1 more
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Financial security of insurance сompanies in the light of the Solvency II directive [PDF]
, 2012 The article presents the issue of financial security of insurance companies in light of the Solvency II Directive. The question of minimum capital requirements for conducting operational activities by insurance and reinsurance companies was also ...
Kafková, Eva, Pukala, Ryszard
core +1 more source
Premium Risk net of Reinsurance: from short-term to medium term assessment [PDF]
, 2019 Solvency II requirements introduced new issues for actuarial risk management in non-life insurance, challenging the market to have a consciousness of its own risk profile, and also investigating the sensitivity of the solvency ratio depending on the ...
Pallaria, Antonio, Savelli, Nino
core +2 more sources
A review of Solvency II: Has it met its objectives?
British Actuarial Journal, 2018 Solvency II is currently one of the most sophisticated insurance regulatory regimes in the world. It is built around the principles of market consistency and embedding strong risk management and governance within insurance companies.
R. A. Rae +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source