The Importance of Anharmonicity and Solvent Effects on the OH Radical Attack on Nucleobases. [PDF]
Ekstrøm AT, Hansen VS, Sauer SPA.
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Dataset for quantum-mechanical exploration of conformers and solvent effects in large drug-like molecules. [PDF]
Medrano Sandonas L +10 more
europepmc +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Solvent Effects on the Phenolic Compounds and Antioxidant Activity Associated with Camellia polyodonta Flower Extracts. [PDF]
Xiang Z +9 more
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Theoretical investigation of penicillamine adsorption on mg<sub>12</sub>o<sub>12</sub> fullerene-like cages considering solvent effects, electronic properties, and potential biomedical applications. [PDF]
Alotaibi HF +8 more
europepmc +1 more source
Profiling of secondary metabolite and CNS modulatory effects of methanolic extract of Bulbophyllum crassipes and its solvent fractions: Evidence from GC–MS, FTIR, behavioral tests, and molecular docking [PDF]
Mohammad Jomel +7 more
openalex +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

