Results 131 to 140 of about 5,393,553 (301)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Ion solvation in aqueous-organic mixtures [PDF]

open access: yes, 2004
The importance of ion solvation in determining the properties of electrolyte solutions in aqueous-organic solvent mixtures is discussed. Solubility measurements are shown to be particularly useful for determining the Gibbs energies of transfer of ions ...
Hefter, G.T., Hefter, G.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Computer-aided theoretical solvent selection using the simplex method based on Hansen solubility parameters

open access: yes, 2018
Solvent selection is a crucial step in all solvent-involved processes. Using the Hansen solubility parameters (HSPs)could provide a solvent/solvent-mixture, but there are two main challenges: 1) What solvents should be selected?
Taherzadeh, Mohammad J   +9 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Dissolution Parameters Reveal Role of Structure and Solvent in Molecular Gelation

open access: yes, 2016
The relationship between thermodynamic dissolution parameters (enthalpy and entropy) and gelation ability was examined for two different classes of compounds in three different solvent systems.
Anne J. McNeil (1432270)   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Microwave-Assisted Extraction (MAE) of Propolis from Tetragonula biroi (Philippine Kiwot Bee) Hives

open access: yesEngineering Proceedings
Propolis is a resinous substance known for its bioactive compounds, such as phenolics and flavonoids, which exhibit antioxidant, antibacterial, and anti-inflammatory benefits.
Nicole D. Llarena   +7 more
doaj   +1 more source

The Use of Solubility Parameters to Select Membrane Materials for Pervaporation of Organic Mixtures [PDF]

open access: yes, 2006
Pevaporation is a method for separating volatile components from liquid mixtures at ambient temperatures. The paint processing industry uses Hansen solubility parameters (HSP) to indicate polymer solubility.
Buckley-Smith, Marion
core  

Multicomponent Solubility Parameters for Single-Walled Carbon Nanotube−Solvent Mixtures

open access: yes, 2016
We have measured the dispersibility of single-walled carbon nanotubes in a range of solvents, observing values as high as 3.5 mg/mL. By plotting the nanotube dispersibility as a function of the Hansen solubility parameters of the solvents, we have ...
David Rickard (737686)   +5 more
core   +1 more source

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