Results 61 to 70 of about 5,393,553 (301)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

EXTRACTION OF STRONTIUM(II) BY CROWN ETHER: INSIGHTS FROM DENSITY FUNCTIONAL CALCULATION

Indonesian Journal of Chemistry, 2012
The structures, energetic and thermodynamic parameters of crown ethers with different cavity size, electron donating/withdrawing substituent groups and donor atoms have been determined with density functional method at B3LYP level of theory in gas and ...
Saprizal Hadisaputra, Harno Dwi Pranowo, Ria Armunanto   +2 more
doaj   +1 more source

The Effects of Solvents and Solid-to-Solvent Ratios on Ultrasound-Assisted Extraction of Carotenoids from Chlorella vulgaris

International Journal of Technology, 2020
Research around using algae as a natural source of carotenoids has been intense in the 21st century, given the wide applications of carotenoids in the pharmaceutical, health, and food industries.
Dianursanti, Aisyah Siregar, Yoshiaki Maeda, Tomoko Yoshino, Tsuyoshi Tanaka   +4 more
doaj   +1 more source

Kinetic Solvent Effects in Organic Reactions [PDF]

, 2018
This article reviews prior work studying reaction kinetics in solution, with the goal of using this information to improve detailed kinetic modeling in the solvent phase.
Belinda, Slakman, Belinda Slakman, Richard West, Richard, West   +3 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Modification of RDX and HMX crystals in procedure of solvent/anti-solvent by statistical methods of Taguchi analysis design and MLR technique

Defence Technology, 2018
Many of the physical and functional properties of RDX and HMX explosives are related to the crystalline structure of these materials. Crystalline defects affect the quality of the explosives. Therefore, in order to enhance the quality of these materials,
Hamid Reza Pouretedal, Sajjad Damiri, Abolfazl Shahsavan   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

AbraLlama: Predicting Abraham Model Solute Descriptors and Modified Solvent Parameters Using Llama

Liquids
This study explores the application of fine-tuned large language models for predicting physicochemical properties, specifically focusing on Abraham model solute descriptors (E, S, A, B, V) and modified solvent parameters (e0, s0, a0, b0, v0).
Andrew S. I. D. Lang, Youngmin Lee
doaj   +1 more source

ION SOLVATION IN SALTS OF BIOLOGICALLY IMPORTANT RARE EARTH METALS WITH AQUEOUS SUGAR ALCOHOL (SORBITOL) MIXED-SOLVENT SYSTEMS

Journal of Taibah University for Science, 2017
Acoustic investigations have examined the salts of rare earth metals, such as lanthanum(III) chloride, in sorbitol-water mixed solvent systems of different concentrations at 303.15 K temperature and 1 atmospheric pressure.
Jayanta Kumar Dash, Susmita Kamila
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source