The Influence of Oxime Selection on the Efficacy of Antidotal Treatment of Soman-Poisoned Rats [PDF]
Acta Medica, 2002 1. The influence of some acetylcholinesterase reactivators (HI-6, obidoxime, pralidoxime) on the efficacy of antidotal treatment to eliminate soman-induced disturbance of respiration and circulation and to protect experimental animals poisoned with ...
Jiří Kassa, Josef Fusek
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Dataset of EEG power integral, spontaneous recurrent seizure and behavioral responses following combination drug therapy in soman-exposed rats [PDF]
Data in Brief, 2019 This article investigated the efficacy of the combination of antiepileptic drug therapy in protecting against soman-induced seizure severity, epileptogenesis and performance deficits.
Lucille A. Lumley +7 more
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Antidotal effect of combinations obidoxime/HI-6 and memantine in mice poisoned with soman, dichlorvos or heptenophos [PDF]
Vojnosanitetski Pregled, 2011 Introduction/Aim. In acute organophosphate poisoning the issue of special concern is the appearance of muscle fasciculations and convulsions that cannot be adequately antagonised by the use of atropine and oxime therapy.
Antonijević Biljana +3 more
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Epilepsia Open, 2021 Objective Cholinergic‐induced status epilepticus (SE) is associated with a loss of synaptic gamma‐aminobutyric acid A receptors (GABAAR) and an increase in N‐methyl‐D‐aspartate receptors (NMDAR) and amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid ...
Lucille A. Lumley +6 more
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Biosilica-nanogold composite: Easy-to-prepare catalyst for soman degradation [PDF]
Arabian Journal of Chemistry, 2019 A very fast single-step biosynthesis of gold nanoparticles (AuNPs) using algal cells of Mallomonas kalinae (MK) is introduced. The average particle size of crystalline AuNPs was approximately 10 nm.
Holišová, Veronika +7 more
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Enhanced Antitumor Activity of Korean Black Soybean Cultivar ‘Soman’ by Targeting STAT-Mediated Aerobic Glycolysis [PDF]
AntioxidantsBlack soybeans have numerous health benefits owing to their high polyphenolic content, antioxidant activity, and antitumor effects. We previously reported that the Korean black soybean cultivar ‘Soman’ possesses higher anthocyanin and isoflavone contents
Su Hwan Park +10 more
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Acta Medica, 2017 Aim: The ability of four newly prepared reversible inhibitors of acetylcholinesterase (6-chlorotacrine, 7-phenoxytacrine, compounds 1 and 2) and currently used carbamate pyridostigmine to increase the resistance of mice against soman and the efficacy of ...
Jiří Kassa +2 more
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Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway [PDF]
FEBS Open BioSoman is an organophosphorus compound that induces neurotoxicity. In addition to its direct toxic effects resulting from acetylcholine accumulation, neurotoxicity may also be exacerbated by inducing endoplasmic reticulum (ER) stress.
Yue Wei +7 more
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Cystamine reduces neurodegeneration and epileptogenesis following soman-induced status epilepticus in rats [PDF]
Experimental Biology and MedicineAcute exposure to a seizure-inducing dose of an organophosphorus nerve agent inhibits acetylcholinesterase, leading to pharmacoresistance if benzodiazepine treatment is delayed.
Abiel K. Biney +6 more
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Further studies of the efficacy of military, commercial and novel skin decontaminants against the chemical warfare agents sulphur mustard, soman and VX [PDF]
, 2019 Background/Aims: Following an incident involving toxic chemicals, deployment of countermeasures before the arrival of specialised services at the scene may provide a “therapeutic” window in which to mitigate skin absorption.
Chilcott, Robert +2 more
core +4 more sources