Results 21 to 30 of about 30,847 (287)
Epilepsia Open, 2023 Despite new antiseizure medications, the development of cholinergic‐induced refractory status epilepticus (RSE) continues to be a therapeutic challenge as pharmacoresistance to benzodiazepines and other antiseizure medications quickly develops.
Jerome Niquet +3 more
doaj +1 more source
Acta Medica, 1997 1. The changes of cholinesterase activity in rabbit blood, peripheral tissues and the central nervous system following transfusion of erythrocytes with soman inhibited acetylcholinesterase were demonstrated. 2. After incubation with soman for 0.5 or 24 h,
Jiří Kassa, Jiří Bajgar, Josef Fusek
doaj +1 more source
Frontiers in Neuroscience, 2021 Nerve agents (NAs) induce a severe cholinergic crisis that can lead to status epilepticus (SE). Current guidelines for treatment of NA-induced SE only include prehospital benzodiazepines, which may not fully resolve this life-threatening condition.
Julia E. Morgan +11 more
doaj +1 more source
Aging Mechanism of Soman Inhibited Acetylcholinesterase [PDF]
The Journal of Physical Chemistry B, 2012 Acetylcholinesterase (AChE) is a crucial enzyme in the cholinergic nervous system that hydrolyzes neurotransmitter acetylcholine (ACh) and terminates synaptic signals. The catalytic serine of AChE can be phosphonylated by soman, one of the most potent nerve agents, and subsequently undergo an aging reaction. This phosphonylation and aging process leads
Gulseher Sarah, Sirin +4 more
openaire +2 more sources
Further studies of the efficacy of military, commercial and novel skin decontaminants against the chemical warfare agents sulphur mustard, soman and VX [PDF]
, 2019 Background/Aims: Following an incident involving toxic chemicals, deployment of countermeasures before the arrival of specialised services at the scene may provide a “therapeutic” window in which to mitigate skin absorption.
Chilcott, Robert +2 more
core +2 more sources
Coding gain in paraunitary analysis/synthesis systems [PDF]
, 1993 A formal proof that bit allocation results hold for the entire class of paraunitary subband coders is presented. The problem of finding an optimal paraunitary subband coder, so as to maximize the coding gain of the system, is discussed.
Soman, Anand K., Vaidyanathan, P. P.
core +1 more source
Linear phase paraunitary filter banks: theory, factorizations and designs [PDF]
, 1993 M channel maximally decimated filter banks have been used in the past to decompose signals into subbands. The theory of perfect-reconstruction filter banks has also been studied extensively. Nonparaunitary systems with linear phase filters have also been
Nguyen, Truong Q. +2 more
core +2 more sources
Development of EM-CCD-based X-ray detector for synchrotron applications [PDF]
, 2014 A high speed, low noise camera system for crystallography and X-ray imaging applications is developed and successfully demonstrated. By coupling an electron-multiplying (EM)-CCD to a 3:1 fibre-optic taper and a CsI(Tl) scintillator, it was possible to ...
A. Warren +14 more
core +1 more source
Inhalation Apparatus for Generating Sarin and Soman Toxic Vapors
Acta Medica, 2003 The developed inhalation system is a dynamic and whole-body exposure model designated for generating sarin or soman vapors. It consists of an evaporating apparatus, an inhalation chamber and a carbon filter.
Lucie Ševelová +2 more
doaj +1 more source
Toxics, 2022 Acute exposure to nerve agents induces status epilepticus (SE), which can cause death or long-term brain damage. Diazepam is approved by the FDA for the treatment of nerve agent-induced SE, and midazolam (MDZ) is currently under consideration to replace ...
Taiza H. Figueiredo +4 more
doaj +1 more source