Results 31 to 40 of about 9,449 (276)

Assessment of the Therapeutic and Anticonvulsive Efficacy of a Drug Combination Consisting of Trihexyphenidyle and HI-6 in Soman-Poisoned Rats

Acta Medica, 2004
1. The influence of two anticholinergic drugs (atropine, trihexyphenidyle) on the effectiveness of antidotal treatment to eliminate soman-induced lethal effects and convulsions was studied in rats. 2.
Jiří Kassa, Ivan Samnaliev
doaj   +1 more source

Midazolam protects B35 neuroblastoma cells through Akt-phosphorylation in reactive oxygen species derived cellular injury [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundSoman, a potent irreversible acetylcholinesterase (AChE) inhibitor, induces delayed neuronal injury by reactive oxygen species (ROS). Midazolam is used in patients with pathologic effects of oxidative stresses such as infection, hemodynamic ...
Won Seog Chong, Chang Lim Hyun, Min Kyu Park, Jeong Min Park, Hyun-Ouk Song, Taejin Park, Young Su Lim, Choon Kyu Cho, Po Soon Kang, Hee Uk Kwon   +9 more
doaj   +1 more source

Monitoring Exposure to Five Chemical Warfare Agents Using the Dried Urine Spot Technique and Liquid Chromatography-Mass Spectrometry/Mass Spectrometry—In Vivo Determination of Sarin Metabolite in Mice

Molecules, 2023
Dried urine spot (DUS) is a micro-sample collection technique, known for its advantages in handling, storage and shipping. It also uses only a small volume of urine, an essential consideration in working with small animals, or in acute medical situations.
Lilach Yishai Aviram, Shai Dagan, Ariel Hindi, Shira Chapman, Rellie Gez, Eyal Drug   +5 more
doaj   +1 more source

The Influence of Anticholinergic Drug Selection on the Effectiveness of Oximes Against Soman-Induced Supralethal Poisoning in Mice

Acta Medica, 2001
1. The influence of anticholinergic drugs (atropine, benactyzine, biperiden) on the efficacy of monopyridinium and bispyridinium oximes (HI-6, BI-6, obidoxime, pralidoxime, methoxime) on soman-induced supralethal poisoning was studied in mice. 2.
Jiří Kassa
doaj   +1 more source

Assessing the Clinical Features and Blood Biochemistries of Acute Organophosphorus Chemical Warfare Agents in Iranian Veterans

International Journal of Medical Toxicology and Forensic Medicine, 2021
Background: Nerve Agents (NAs) are a chemical weapons, and their use is prohibited. They were used for numerous-times in the warfare of Iraq against Iran.
khosrow Agin , Babak Mostafazadeh
doaj   +1 more source

Antimicrobial Activity and Degradation Ability Study on Nanoparticle-Enriched Formulations Specially Designed for the Neutralization of Real and Simulated Biological and Chemical Warfare Agents

Pharmaceuticals, 2022
The present work reveals a comprehensive decontamination study on real and simulated biological and chemical warfare agents (BCWA). The emphasis was on evaluating the antimicrobial activity against real biological warfare agents, such as Bacillus ...
Raluca-Elena Ginghina, Gabriela Toader, Munizer Purica, Adriana-Elena Bratu, Claudiu Lazaroaie, Tudor-Viorel Tiganescu, Ramona-Elena Oncioiu, George-Ovidiu Iorga, Florina-Lucica Zorila, Mihai Constantin, Gabriel Craciun, Florin Comanescu, Cosmin Romanitan   +12 more
doaj   +1 more source

Retention of Soman in Rats, Guinea-pigs and Marmosets: Species-dependent Effects of the Soman Simulator, Pinacolyl Dimethylphosphinate (PDP)

, 1988
Whether the temporary retention of intact soman in the rat and its subsequent delivery from tissues into the circulation of the blood is also demonstrable in guinea-pigs and marmosets has been investigated as was whether the soman simulator PDP ...
O L Wolthuis, H J van der Wiel, H P M van Helden   +2 more
core   +1 more source

Enhanced Antitumor Activity of Korean Black Soybean Cultivar ‘Soman’ by Targeting STAT-Mediated Aerobic Glycolysis

Antioxidants
Black soybeans have numerous health benefits owing to their high polyphenolic content, antioxidant activity, and antitumor effects. We previously reported that the Korean black soybean cultivar ‘Soman’ possesses higher anthocyanin and isoflavone contents
Su Hwan Park, Jeong Hyun Seo, Min Young Kim, Hye Jin Yun, Beom Kyu Kang, Jun Hoi Kim, Su Vin Heo, Yeong Hoon Lee, Hye Rang Park, Man Soo Choi, Jong-Ho Lee   +10 more
doaj   +1 more source

Administration of (−)-phenserine prior to but not after soman protects against soman-induced mortality.

, 2014
Rats were administered (−)-phenserine, posiphen or saline 4 hr (A), or 30 min (B) prior to or 5 min (C) or 30 min (D) after soman. In the 4 hr pretreatment groups of animals, 12 rats died in the posiphen group and 11 rats died in the control group. There
Cynthia Chen (501614), David M. Jacobowitz (582272), Kevin Iskandar (582269), Ann M. Marini (156176), Qian-Sheng Yu (250649), Hongna Pan (582268), Wei Wu (27708), John H. McDonough (582273), Jun Chen (4238), Tetsade Piermartiri (582271), Jeffrey He (582270), Nigel H. Greig (214075)   +11 more
core   +1 more source

Dataset for Milling cutter fault diagnosis using unsupervised learning on small data: A robust and autonomous framework

, 2023
<p>This is the dataset related to the publication titled: </p> <pre>Milling cutter fault diagnosis using unsupervised learning on small data: A robust and autonomous framework<br><br>Published in the journal ...
Soman, Rohan
core   +1 more source