Results 171 to 180 of about 10,841,366 (345)

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

Science, 2017
C. Tomasetti, Lu Li, B. Vogelstein
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Neural Network-Aided Milk Somatic Cell Count Increase Prediction. [PDF]

Vet Sci
Nagy SÁ, Csabai I, Varga T, Póth-Szebenyi B, Gábor G, Solymosi N.   +5 more
europepmc   +1 more source

A NEW SYNDROME OF FAMILIAL PANCREATIC AGENESIS: THE ROLE OF INSULIN AND GLUCAGON IN SOMATIC AND CELL GROWTH [PDF]

, 1974
W. G. Sherwood, G. W. Chance, Donald E. Hill, Donald Fraser   +3 more
openalex   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

H3K9me3 and H3K27me3 are epigenetic barriers to somatic cell nuclear transfer in rabbits. [PDF]

Am J Transl Res
Gao Y, Wu F, Tang D, Chen X, Chen Q, Chen Y, Fang K, Chen W, Du F, Liu Z.   +9 more
europepmc   +1 more source

Somatic Hybrid Cell Formation by Viral Genome-Free Envelopes Reassembled from Solubilized HVJ (Sendai Virus)

, 1975
Yoshio Okada, Yasuhiro Hosaka, Kazufumi Shimizu, Katsuaki Matsui   +3 more
openalex   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment. [PDF]

Ibrain
Li X, Fang K, Wang F.
europepmc   +1 more source

Association of Homologous Chromosomes in the Somatic Cells of <i>Ornithogalum virens</i>

, 1973
K. P. S. Chauhan
openalex   +2 more sources