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Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9 [PDF]
, 2019 Curiel, David T +5 more
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Transgenic Bovine Nuclear Transfer Embryos from Adult Somatic Cell Lines*
, 2003 Sezen Arat
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Somatic cell nuclear transfer in zebrafish
Nature Methods, 2009We developed a method for somatic cell nuclear transfer in zebrafish using laser-ablated metaphase II eggs as recipients, the micropyle for transfer of the nucleus and an egg activation protocol after nuclear reconstruction. We produced clones from cells of both embryonic and adult origins, although the latter did not give rise to live adult clones.
Kannika, Siripattarapravat +4 more
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Progress in Human Somatic-Cell Nuclear Transfer
New England Journal of Medicine, 2005The efficiency of deriving blastocysts through the nuclear transfer of embryonic stem cells has been improved by a factor of more than 14.
Anthony C F Perry
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Australian Journal of Experimental Agriculture, 2004
Abstract The methods of nuclear transfer in mammals have created many new opportunities in biology, medicine, and agriculture. Potential uses of these technologies include production of animal organs and tissues for transplantation to human patients (xenotransplantation), improvement of livestock, provision of human cells for treatment ...
Paul De Sousa +5 more
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Abstract The methods of nuclear transfer in mammals have created many new opportunities in biology, medicine, and agriculture. Potential uses of these technologies include production of animal organs and tissues for transplantation to human patients (xenotransplantation), improvement of livestock, provision of human cells for treatment ...
Paul De Sousa +5 more
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Somatic Cell Nuclear Transfer in Pigs
2023Somatic cell nuclear transfer (SCNT) has been successfully applied to clone animals of several species. Pigs are one of the main livestock species for food production and are also important for biomedical research due to their physiopathological similarities with humans.
Werner G, Glanzner +2 more
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Somatic Cell Nuclear Transfer in Rabbits
2023Somatic cell nuclear transfer (SCNT) is a technology that enables differentiated somatic cells to acquire a totipotent state, thus making it of great value in developmental biology, biomedical research, and agricultural applications. Rabbit cloning associated with transgenesis has the potential to improve the applicability of this species for disease ...
Pengxiang, Qu, Wenbin, Cao, Enqi, Liu
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Cloning by somatic cell nuclear transfer
BioEssays, 1998The birth of the first cloned mammals, produced by the introduction of somatic cell nuclei into enucleated oocytes, was an impressive and surprising development. Although the ethical debate has been intense, the important scientific questions raised by this work have been inadequately discussed and are still unresolved.
J, Fulka, N L, First, P, Loi, R M, Moor
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Bovine Somatic Cell Nuclear Transfer
2010Somatic cell nuclear transfer (SCNT) is a technique by which the nucleus of a differentiated cell is introduced into an oocyte from which its genetic material has been removed by a process called enucleation. In mammals, the reconstructed embryo is artificially induced to initiate embryonic development (activation).
Pablo J, Ross, Jose B, Cibelli
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