Results 261 to 270 of about 63,552 (337)

Direct Surface Modification of the Epidermis Using Mussel‐Inspired Polydopamine with Multiple Anti‐Biofouling Functions

Advanced Healthcare Materials, EarlyView.
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee, Hanna Lee, Jang Hwan Kim, Sungwook Park, Young Taek Oh, Hayoung Choi, Jeong‐Min Kim, Hye‐Jun Jo, Jun Hyun Park, Ho Jun Jin, Kwan Hyi Lee, Seung Ho Han, Hojun Kim, Jun Kyun Oh, Bong Hoon Kim   +14 more
wiley   +1 more source

Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells

Advanced Healthcare Materials, EarlyView.
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd, Xinyu Ma, Zahra Zohali, Lieve L. Oudejans, Emmanouil Kyrloglou, Marc. C. A. Stuart, Wouter H. Roos, Jan Jacob Schuringa, Anna Salvati   +8 more
wiley   +1 more source

Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation

Advanced Healthcare Materials, EarlyView.
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng, Li‐Ling Chen, Guan‐Jhong Tseng, Jun‐Xuan Huang, Yen‐Jing Ting, Po‐Han Chiang   +5 more
wiley   +1 more source

Genomic Stability of Lyophilized Sheep Somatic Cells before and after Nuclear Transfer

, 2013
Domenico Iuso, Marta Czernik, Fiorella Di Egidio, Silvestre Sampino, Federica Zacchini, M. Bochenek, Z. Smorąg, Jacek A. Modliński, Grazyna Ptak, Pasqualino Loi   +9 more
openalex   +2 more sources

Tumor‐Targeted Exosome‐Based Heavy Atom‐Free Nanosensitizers With Long‐Lived Excited States for Safe and Effective Sono‐Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen, Thuy Giang Nguyen Cao, Hyunsun Jeong, Quan Truong Hoang, Binh T. T. Pham, Jieun Bang, Chang Woo Koh, Ji Hee Kang, Jeong Hyun Lee, Xiaofeng Wu, Won Jong Rhee, Young Tag Ko, K. M. K. Swamy, Sungnam Park, JaeHong Park, Min Suk Shim, Juyoung Yoon   +16 more
wiley   +1 more source

Mesoporous Fe3O4 Nanoparticles Loaded with IR‐820 for Antibacterial Activity via Magnetic Hyperthermia Combined with Photodynamic Therapy

Advanced Healthcare Materials, EarlyView.
This study addresses bacterial biofilm resistance by developing mesoporous Fe3O4 nanoparticles loaded with photosensitizer IR‐820, enabling combined antimicrobial photodynamic therapyand magnetic hyperthermia therapy. The system achieves magnetic targeting, heat‐triggered drug release under alternating magnetic fields, and near‐infrared‐induced ROS ...
Yuange Li, Song Xue, Hong Sung Min, Chen Chen, Liheng Lu, Zhiheng Chen, Haojie Shan, Fuli Yin, Xiaowei Yu   +8 more
wiley   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha, Sneha Kollenchery Ramanathan, Kristin Oskarsdotter, Fatemeh Rasti Boroojeni, Aleksandra Zielińska, Sajjad Naeimipour, Philip Lifwergren, Nina Reustle, Lauren Roberts, Annika Starkenberg, Gunnar Kratz, Peter Apelgren, Karin Säljö, Jonathan Rakar, Lars Kölby, Daniel Aili, Johan Junker   +16 more
wiley   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim, Woochan Kim, Harshita Sharma, Shinyull Lee, Chaeyeon Park, Sunho Park, Chan Yeong Heo, Jangho Kim   +7 more
wiley   +1 more source