Results 41 to 50 of about 49,767 (265)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Biotecnología Vegetal, 2009 Somatic embryogenesis in papaya has been subjected to many researches. However, the effect of ex vitro and in vitro environment on this process has been little studied.
Laisyn Posada-Pérez +4 more
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A Carrot Somatic Embryo Mutant Is Rescued by Chitinase [PDF]
The Plant Cell, 1992 At the nonpermissive temperature, somatic embryogenesis of the temperature-sensitive (ts) carrot cell mutant ts11 does not proceed beyond the globular stage. This developmental arrest can be lifted by the addition of proteins secreted by wild-type cells to the culture medium.
de Jong, A.J. +6 more
openaire +4 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
THE BIOTECHNOLOGY OF EMBRYOGENIC CELL LINES OBTAINING AND PLANTLETS OF CONIFEROUS SPECIES IN SIBERIA IN CULTURE IN VITRO [PDF]
Journal of Stress Physiology & Biochemistry, 2012 Experiments of culturing the immature isolated embryos and megagamethophytes of Siberian coniferous species were carried out on different modified media: ½ LV medium for Pinus sibirica and Pinus pumila, MSG and AI media (patent № 2431651) for Larix ...
Tretiakova I. +4 more
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Efficient plant regeneration from embryogenic cell suspension cultures of Euonymus alatus
Scientific Reports, 2021 To establish an efficient plant regeneration system from cell suspension cultures of Euonymus alatus, embryogenic callus formation from immature embryos was investigated. The highest frequency of embryogenic callus formation reached 50% when the immature
Hyun-A Woo +9 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Biotecnología Vegetal, 2013 Low germination of somatic embryos in S. mahagoni is a problem that needs solutions. Its cause is related to the low level of embryo maturation. The objective of this research was to determine the effect of different concentrations of sorbitol and 6-BAP ...
Raúl Barbón +4 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Biotecnología Vegetal, 2011 Soybean is genotype-dependent as it has been shown. This has lead to work on new protocols for plant regeneration. This research aimed to achieve growth and germination of somatic embryos in the Cuban varieties Incasoy-1 and Incasoy-27.
Idalmis Bermúdez-Caraballoso +6 more
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