Results 71 to 80 of about 57,406 (251)
Pharmaceuticals, 2019 As the first radiopharmaceutical for Peptide Receptor Radionuclide Therapy (PRRT), Lutathera® was approved by the EMA in 2017 and the FDA in 2018 for the treatment of somatostatin receptor (SSTR) positive gastroenteropancreatic neuroendocrine tumors.
Ute Hennrich, Klaus Kopka
doaj +1 more source
Radiology Case Reports, 2020 Lung neuroendocrine neoplasms (NENs) encompass the low-, intermediate-, and high-grade entities. Differentiated NENs overexpress somatostatin receptors, which are targeted by 68Ga-DOTA-conjugated peptides in molecular imaging with positron emission ...
Gaia Ninatti +4 more
doaj +1 more source
Focal Spot, Fall/Winter 1993 [PDF]
, 1993 https://digitalcommons.wustl.edu/focal_spot_archives/1065/thumbnail ...
core +1 more source
Somatostatin/somatostatin receptor signalling: Phosphotyrosine phosphatases [PDF]
Molecular and Cellular Endocrinology, 2008 Activation of phosphotyrosine phosphatases (PTPs) by somatostatin receptor (SSTR) represents one of the main intracellular mechanisms involved in the antiproliferative effect of somatostatin (SST) and analogues. Since their molecular cloning, the role of PTPs is emerging as a major regulator of different cell functions including cell proliferation ...
openaire +3 more sources
Journal of the Science of Food and Agriculture, EarlyView.Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen +2 more
wiley +1 more source
A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. [PDF]
, 2015 Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in ...
Blasio, Angelo +13 more
core +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Somatostatinergic systems: an update on brain functions in normal and pathological aging
Frontiers in Endocrinology, 2012 Somatostatin is highly expressed in mammalian brain and is involved in many brain functions such as motor activity, sleep, sensory and cognitive processes. Five somatostatin receptors have been described: sst1, sst2 (A and B), sst3 to 5, all belonging to
Guillaume eMartel +7 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
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Medicinal Research Reviews, EarlyView.ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg +2 more
wiley +1 more source