Results 31 to 40 of about 520,750 (256)

Современные формы бытования этномузыкальных традицийсибирских татар [PDF]

open access: yesВестник музыкальной науки, 2020
В настоящее время татарское этномузыкознание стремится рассматривать татарскую музыкальную культуру как синтез регионально-диалектологических компонентов различных этнографических и локально-территориальных групп, что определяет необходимость восприятия ...
Нургаянова, Неля Хабибулловна
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

open access: yesScientific Reports
We developed a CancerMaster-targeted next generation sequencing (NGS) panel covering 524 key genes specifically designed for the multidimensional molecular profiling of solid tumors.
Jingmin Che   +11 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Microvascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Hypoxia drives sickle cell disease (SCD) by inducing sickle cell haemoglobin to polymerize and deform red blood cells (RBC) into the sickle shape.
William H. Nugent   +4 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

Performance of microbial desalination cells with different cathode types in treating saline wastewater

open access: yesScientific Reports
Microbial desalination cells (MDCs), as an emerging desalination technology, have attracted increasing attention in recent years due to their ability to simultaneously achieve salt removal and wastewater treatment without the need for external energy ...
Hongsheng Jia   +5 more
doaj   +1 more source

Gınâdan Semâ’ya: Fakihlerin Tasavvuf Mûsikisine Bakışı

open access: yesHitit İlahiyat Dergisi, 2021
Müzik, tasavvuf ve fıkıh gibi iki farklı şer‘î ilmin İslam dinine olan bakışını ve yaklaşımını ortaya koymak bakımından oldukça uygun bir konudur. Kimi fakihler tarafından dini kaygılar gözetilerek uzak durulması ve hatta yasak/haram olduğu düşünülen ...
Fatih Orhan
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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