Results 51 to 60 of about 245,160 (297)

Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance

Advanced Science, EarlyView.
By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam, Yi Chen, Héctor Estrada, Ananya Amitabh, Amirreza Aghakhani, Metin Sitti, Daniel Razansky   +6 more
wiley   +1 more source

Discrete Adjoint Optimization Method for Low-Boom Aircraft Design Using Equivalent Area Distribution

Aerospace
This paper introduces a low-boom aircraft optimization design method guided by equivalent area distribution, which effectively improves the intuitiveness and refinement of inverse design. A gradient optimization method based on discrete adjoint equations
Chuang Ma, Jiangtao Huang, Daochun Li, Jun Deng, Gang Liu, Lin Zhou, Cheng Chen   +6 more
doaj   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Sonic Boom Assessment [PDF]

The Journal of the Acoustical Society of America, 1964
The difficulties of assessing the significance of sonic booms and the public's reaction to them is causing great concern. The paper describes some recent researches carried out at the University of Southampton on the relevant reactions of persons to transient sounds of the sonic-boom type, in which the various characteristics of the boom are altered ...
openaire   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self‐Assembled Polydiacetylene‐Silk Core‐Shell Vesicles

Advanced Science, EarlyView.
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti, Giulia Guidetti, Elisabetta Ruggeri, Terri Lyne Carrington, Fiorenzo G. Omenetto   +4 more
wiley   +1 more source

Numerical analysis of stagger Supersonic biplane at off-design condition with trailing edge flap [PDF]

FME Transactions, 2023
Supersonic biplanes can achieve low-boom and low-drag supersonic flights. In the present study, aerodynamic analysis of a two-dimensional stagger Bussmann biplane (staggered upper element by 0.5c) at zero degrees angle of attack with trailing edge flap ...
Patidar Vijay Kumar, Joshi Sudhir
doaj  

Summary of Propagation Cases of the Second AIAA Sonic Boom Prediction Workshop

Journal of Aircraft, 2019
A summary is provided for the propagation portion of the second AIAA Sonic Boom Prediction Workshop, held 8 January 2017 in conjunction with the AIAA SciTech 2017 Conference.
Sriram K. Rallabhandi, A. Loubeau
semanticscholar   +1 more source

Estimated ambient sonic boom metric levels and X-59 signal-to-noise ratios across the USA

, 2020
NASA is building the X-59 Quiet Supersonic Technology aircraft to produce low noise sonic booms for a series of community noise surveys across the USA.
W. J. Doebler
semanticscholar   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source