Results 211 to 220 of about 116,918 (241)

Comparative genomics on Sonic Hedgehog orthologs

Oncology Reports, 2005
Sonic hedgehog (SHH), Indian hedgehog (IHH), and Desert hedgehog (DHH) are key molecules for the integrome network in oncology and regenerative medicine. Soluble Hedgehog ligands bind to Patched receptor to activate Smoothened seven-transmembrane receptor with Frizzled domain. KIF27 and KIF7 are human homologs of Drosophila Costal-2 (Cos2), associating
Yuriko, Katoh, Masaru, Katoh
openaire   +2 more sources

Sonic hedgehog is essential to foregut development

Nature Genetics, 1998
Congenital malformation of the foregut is common in humans, with an estimated incidence of 1 in 3000 live births, although its aetiology remains largely unknown. Mice with a targeted deletion of Sonic hedgehog (Shh) have foregut defects that are apparent as early as embryonic day 9.5, when the tracheal diverticulum begins to outgrow.
Y, Litingtung, L, Lei, H, Westphal, C, Chiang   +3 more
openaire   +2 more sources

The role of Hedgehog acyltransferase in Sonic hedgehog signalling

2012
Protein acyltransferases (PATs), a group of enzymes catalysing fatty acylation of a variety of proteins, play an important role in protein sorting and signalling in the cell. In the Hedgehog (Hh) signalling pathway the PAT Hedgehog acyltransferase (Hhat) is responsible for addition of a palmitic acid to the N-terminal cysteine of Hh proteins.
openaire   +2 more sources

Sonic hedgehog

AfCS-Nature Molecule Pages, 2006
Samer Singh, John Goetz, David Robbins
openaire   +1 more source

Sonic Hedgehog Regulates Bone Fracture Healing

International Journal of Molecular Sciences, 2020
Akihiro Hosoya, Tsuyoshi Shimo, Hiroaki Takebe   +2 more
exaly  

Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice

Developmental Cell, 2022
Brian Harfe, Susan Mackem, Jianjian Zhu   +2 more
exaly  

Dispatching Sonic Hedgehog: Molecular Mechanisms Controlling Deployment

Trends in Cell Biology, 2019
Stacey K Ogden, Eric Hall
exaly  

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors

Cancers, 2016
Carpenter R L, Hui-Wen Lo, Michael Chan   +2 more
exaly  

Topical Sonic Hedgehog Gene Therapy Accelerates Wound Healing in Diabetes by Enhancing Endothelial Progenitor Cell–Mediated Microvascular Remodeling

Circulation, 2006
Masaaki Ii, Jun Asai, Hideya Takenaka
exaly  

Axial (HNF3β) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter

EMBO Journal, 1997
Philip William Ingham, Patrick Blader, Bei-En Chang   +2 more
exaly