Results 271 to 280 of about 66,215 (305)

Sonic Hedgehog on Microparticles and Neovascularization

2012
Neovascularization represents a pivotal process consisting in the development of vascular network during embryogenesis and adult life. Postnatally, it arises mainly through angiogenesis, which has physiological and pathological roles in health and disease.
Soleti, Raffaella, Martinez, Maria Carmen   +1 more
openaire   +2 more sources

Sonic hedgehog relates to colorectal carcinogenesis

Journal of Gastroenterology, 2009
The activation of Hedgehog signaling, which is critical to normal mammalian gastrointestinal development, is implicated in the development of various tumors, including colorectal cancer. In the pancreas, a precursor lesion overexpresses the Sonic hedgehog (Shh) when compared with normal tissue and cancer.
Kozo, Yoshikawa, Mitsuo, Shimada, Hidenori, Miyamoto, Jun, Higashijima, Tomohiko, Miyatani, Masanori, Nishioka, Nobuhiro, Kurita, Takashi, Iwata, Hisanori, Uehara   +8 more
openaire   +2 more sources

[Sonic hedgehog].

Clinical calcium, 2005
We investigated ectopic cartilage and bone formation induced by transplantation of cells which were transfected with Sonic hedgehog (Shh) cDNA encoding amino-terminal peptide for gene therapy in bone regeneration. These results indicated Shh regulated early chondrogenesis and stimulation of prechondrocytes, and consequently the synergistic effects of ...
Hisashi, Hattori, Hideki, Mizutani, Minoru, Ueda   +2 more
openaire   +1 more source

Comparative genomics on Sonic Hedgehog orthologs

Oncology Reports, 2005
Sonic hedgehog (SHH), Indian hedgehog (IHH), and Desert hedgehog (DHH) are key molecules for the integrome network in oncology and regenerative medicine. Soluble Hedgehog ligands bind to Patched receptor to activate Smoothened seven-transmembrane receptor with Frizzled domain. KIF27 and KIF7 are human homologs of Drosophila Costal-2 (Cos2), associating
Yuriko, Katoh, Masaru, Katoh
openaire   +2 more sources

Sox2 Requirement in Sonic Hedgehog-Associated Medulloblastoma

Cancer Research, 2013
Abstract The transcription factor Sox2 has been shown to play essential roles during embryonic development as well as in cancer. To more precisely understand tumor biology and to identify potential therapeutical targets, we thoroughly investigated the expression and function of Sox2 in medulloblastoma, a malignant embryonic brain ...
Ahlfeld, J, FAVARO, REBECCA, Pagella, P, Kretzschmar, H, NICOLIS, SILVIA KIRSTEN, Schüller, U.   +5 more
openaire   +2 more sources

Sonic hedgehog

AfCS-Nature Molecule Pages, 2006
Samer Singh, John Goetz, David Robbins
openaire   +1 more source

Sonic Hedgehog (Shh)

2012
Kaitlyn Ryan, Chin Chiang
openaire   +1 more source

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

Nature Reviews Clinical Oncology, 2015
Lucio Miele, Sherry X Yang, S Percy Ivy
exaly  

The mechanisms of Hedgehog signalling and its roles in development and disease

Nature Reviews Molecular Cell Biology, 2013
James Briscoe
exaly  

Sonic Hedgehog

2008
openaire   +1 more source