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Sonic Hedgehog Signaling and the Developing Tooth
2004Publisher Summary This chapter discusses the sonic hedgehog (Shh) signaling and the developing tooth. The signaling peptide encoded by the Shh gene has a diverse and wide range of function during normal vertebrate development, and this pathway is active in the developing tooth.
Cobourne, M T, Sharpe, P T
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2009
The Hedgehog (Hh) Pathway, originally identified in Drosophila, [1–4] is a highly conserved signaling pathway which orchestrates multiple, disparate aspects of embryogenesis, development and tissue remodeling in a wide spectrum of systems [5–8]. This is usually accomplished by autocrine/paracrine signaling and aims to control the size and localization ...
Alessia Omenetti, Anna Mae Diehl
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The Hedgehog (Hh) Pathway, originally identified in Drosophila, [1–4] is a highly conserved signaling pathway which orchestrates multiple, disparate aspects of embryogenesis, development and tissue remodeling in a wide spectrum of systems [5–8]. This is usually accomplished by autocrine/paracrine signaling and aims to control the size and localization ...
Alessia Omenetti, Anna Mae Diehl
openaire +1 more source
The role of sonic hedgehog in vertebrate development
Matrix Biology, 1997Members of the hedgehog family are important signalling molecules during embryonic development. One member, Sonic hedgehog, is expressed in embryonic structures such as the zone of polarizing activity in the posterior limb bud, the notochord, and the floor plate of the neural tube, where it plays a role in patterning of the embryo.
M, Weed, S, Mundlos, B R, Olsen
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The role of Hedgehog acyltransferase in Sonic hedgehog signalling
2012Protein acyltransferases (PATs), a group of enzymes catalysing fatty acylation of a variety of proteins, play an important role in protein sorting and signalling in the cell. In the Hedgehog (Hh) signalling pathway the PAT Hedgehog acyltransferase (Hhat) is responsible for addition of a palmitic acid to the N-terminal cysteine of Hh proteins.
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Proceedings of the National Academy of Sciences of the United States of America, 2023
Jennifer E Neil +2 more
exaly
Jennifer E Neil +2 more
exaly
Axial (HNF3β) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter
EMBO Journal, 1997Bei-En Chang +2 more
exaly
Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy
EMBO Reports, 2016Caixia Jia +2 more
exaly

