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Sonic Hedgehog Signaling and the Developing Tooth

2004
Publisher Summary This chapter discusses the sonic hedgehog (Shh) signaling and the developing tooth. The signaling peptide encoded by the Shh gene has a diverse and wide range of function during normal vertebrate development, and this pathway is active in the developing tooth.
Cobourne, M T, Sharpe, P T
openaire   +3 more sources

Sonic Hedgehog Pathway

2009
The Hedgehog (Hh) Pathway, originally identified in Drosophila, [1–4] is a highly conserved signaling pathway which orchestrates multiple, disparate aspects of embryogenesis, development and tissue remodeling in a wide spectrum of systems [5–8]. This is usually accomplished by autocrine/paracrine signaling and aims to control the size and localization ...
Alessia Omenetti, Anna Mae Diehl
openaire   +1 more source

The role of sonic hedgehog in vertebrate development

Matrix Biology, 1997
Members of the hedgehog family are important signalling molecules during embryonic development. One member, Sonic hedgehog, is expressed in embryonic structures such as the zone of polarizing activity in the posterior limb bud, the notochord, and the floor plate of the neural tube, where it plays a role in patterning of the embryo.
M, Weed, S, Mundlos, B R, Olsen
openaire   +2 more sources

The role of Hedgehog acyltransferase in Sonic hedgehog signalling

2012
Protein acyltransferases (PATs), a group of enzymes catalysing fatty acylation of a variety of proteins, play an important role in protein sorting and signalling in the cell. In the Hedgehog (Hh) signalling pathway the PAT Hedgehog acyltransferase (Hhat) is responsible for addition of a palmitic acid to the N-terminal cysteine of Hh proteins.
openaire   +2 more sources

Sonic hedgehog

AfCS-Nature Molecule Pages, 2006
Samer Singh, John Goetz, David Robbins
openaire   +1 more source

TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system

Proceedings of the National Academy of Sciences of the United States of America, 2023
Jennifer E Neil   +2 more
exaly  

Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy

EMBO Reports, 2016
Caixia Jia   +2 more
exaly  

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