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Sonodynamic therapy-derived multimodal synergistic cancer therapy
Cancer Letters, 2021Sonodynamic therapy (SDT) represents a promising modality that provides the possibility of non-invasively eliminating solid tumors in a site-directed manner. In light of the complexity and heterogeneity of tumors, more and more studies are attempting to combine SDT with other therapeutic methods so as to achieve better tumor treatment effect, which ...
Mimi, Xu +6 more
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Metal Complexes for Cancer Sonodynamic Therapy
ChemBioChem, 2022AbstractSonodynamic therapy (SDT) for cancer treatment is gaining attention owing to its non‐invasive property and ultrasound‘s (US) deep tissue penetration ability. In SDT, US activates the sonosensitizer at the target deep‐seated tumors to generate reactive oxygen species (ROS), which ultimately damage tumors.
Arif Ali Mandal +3 more
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Advanced biotechnology-assisted precise sonodynamic therapy
Chemical Society Reviews, 2021Herein, we provide the enhancement of SDT effect through elaborate strategies including the design and modification of sonosensitizers, the combination other therapy modalities, and molecular imaging-guided SDT for precise treatment.
Yi Zhang +9 more
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Stimuli responsive nanosonosensitizers for sonodynamic therapy
Journal of Controlled Release, 2023Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth, high spatiotemporal selectivity, and noninvasive therapeutic method.
Zeyu, Jiang, Wenjing, Xiao, Qinrui, Fu
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Ultrasonics, 2008
Recently, there have been numerous reports on the application of non-thermal ultrasound energy for treating various diseases in combination with drugs. Furthermore, the introduction of microbubbles and nanobubbles as carriers/enhancers of drugs has added a whole new dimension to therapeutic ultrasound.
Katsuro, Tachibana +2 more
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Recently, there have been numerous reports on the application of non-thermal ultrasound energy for treating various diseases in combination with drugs. Furthermore, the introduction of microbubbles and nanobubbles as carriers/enhancers of drugs has added a whole new dimension to therapeutic ultrasound.
Katsuro, Tachibana +2 more
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Multifunctional sonosensitizers in sonodynamic cancer therapy
Chemical Society Reviews, 2020Phototherapy, including photodynamic therapy and photothermal therapy, has the potential to treat several types of cancer.
Subin Son +10 more
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SONODYNAMIC THERAPY (SDT) AND GENE THERAPY
CARDIOMETRY, 2023One in Four Deaths in Japan Caused by Cancer. Cancer is the most common cause of death for Japanese people who are 40 and over, while suicide is the leading cause among young people.
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Studies On Sonodynamic Cancer Therapy
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1992Chemical agents such as hematoporphyrin have been found to have a sonochemical activity to induce anti-tumor effects. The same kind of sonochemical reactions producing active oxygen species has been demonstrated to be localized with a highly focused ultrasound in a specially developed tissue-mimicking phantom.
null Umemura +4 more
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Free Radical Intermediates in Sonodynamic Therapy
Annals of the New York Academy of Sciences, 2000Abstract: Current understanding of the mechanism of sonodynamic action (i.e. the ultrasound‐dependent enhancement of the cytotoxic action of certain drugs ‐ sonosensitizers) with potential applications for cancer therapy is presented. The experimental evidence suggests that sonosensitization is due to the chemical activation of sonosensitizers inside ...
V, Misík, P, Riesz
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Sonochemistry of sonodynamic therapy
The Journal of the Acoustical Society of America, 1998Sonodynamic therapy is a promising modality for cancer treatment based on the synergistic effect of cell killing by a combination of drugs (sonosensitizers) and ultrasound. The effectiveness of sonodynamic therapy was demonstrated in cell studies and in tumor-bearing animals.
Peter Riesz, Vladimir Misik
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