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Sonodynamic therapy-derived multimodal synergistic cancer therapy

Cancer Letters, 2021
Sonodynamic therapy (SDT) represents a promising modality that provides the possibility of non-invasively eliminating solid tumors in a site-directed manner. In light of the complexity and heterogeneity of tumors, more and more studies are attempting to combine SDT with other therapeutic methods so as to achieve better tumor treatment effect, which ...
Mimi, Xu   +6 more
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Metal Complexes for Cancer Sonodynamic Therapy

ChemBioChem, 2022
AbstractSonodynamic therapy (SDT) for cancer treatment is gaining attention owing to its non‐invasive property and ultrasound‘s (US) deep tissue penetration ability. In SDT, US activates the sonosensitizer at the target deep‐seated tumors to generate reactive oxygen species (ROS), which ultimately damage tumors.
Arif Ali Mandal   +3 more
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Advanced biotechnology-assisted precise sonodynamic therapy

Chemical Society Reviews, 2021
Herein, we provide the enhancement of SDT effect through elaborate strategies including the design and modification of sonosensitizers, the combination other therapy modalities, and molecular imaging-guided SDT for precise treatment.
Yi Zhang   +9 more
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Stimuli responsive nanosonosensitizers for sonodynamic therapy

Journal of Controlled Release, 2023
Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth, high spatiotemporal selectivity, and noninvasive therapeutic method.
Zeyu, Jiang, Wenjing, Xiao, Qinrui, Fu
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Sonodynamic therapy

Ultrasonics, 2008
Recently, there have been numerous reports on the application of non-thermal ultrasound energy for treating various diseases in combination with drugs. Furthermore, the introduction of microbubbles and nanobubbles as carriers/enhancers of drugs has added a whole new dimension to therapeutic ultrasound.
Katsuro, Tachibana   +2 more
openaire   +2 more sources

Multifunctional sonosensitizers in sonodynamic cancer therapy

Chemical Society Reviews, 2020
Phototherapy, including photodynamic therapy and photothermal therapy, has the potential to treat several types of cancer.
Subin Son   +10 more
openaire   +2 more sources

SONODYNAMIC THERAPY (SDT) AND GENE THERAPY

CARDIOMETRY, 2023
One in Four Deaths in Japan Caused by Cancer. Cancer is the most common cause of death for Japanese people who are 40 and over, while suicide is the leading cause among young people.
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Studies On Sonodynamic Cancer Therapy

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1992
Chemical agents such as hematoporphyrin have been found to have a sonochemical activity to induce anti-tumor effects. The same kind of sonochemical reactions producing active oxygen species has been demonstrated to be localized with a highly focused ultrasound in a specially developed tissue-mimicking phantom.
null Umemura   +4 more
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Free Radical Intermediates in Sonodynamic Therapy

Annals of the New York Academy of Sciences, 2000
Abstract: Current understanding of the mechanism of sonodynamic action (i.e. the ultrasound‐dependent enhancement of the cytotoxic action of certain drugs ‐ sonosensitizers) with potential applications for cancer therapy is presented. The experimental evidence suggests that sonosensitization is due to the chemical activation of sonosensitizers inside ...
V, Misík, P, Riesz
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Sonochemistry of sonodynamic therapy

The Journal of the Acoustical Society of America, 1998
Sonodynamic therapy is a promising modality for cancer treatment based on the synergistic effect of cell killing by a combination of drugs (sonosensitizers) and ultrasound. The effectiveness of sonodynamic therapy was demonstrated in cell studies and in tumor-bearing animals.
Peter Riesz, Vladimir Misik
openaire   +1 more source

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