Results 201 to 210 of about 2,350,497 (231)

Probing the mechanisms of sonodynamic therapy

The Journal of the Acoustical Society of America, 2022
Drugs that can be activated by a physical stimulus at a target site offer great potential for limiting toxic side effects, e.g., in cancer therapy. In photodynamic therapy, light is used as the stimulus, but clinical applications are limited due to the poor penetration of light in tissue.
openaire   +1 more source

Advances in Sonodynamic Therapy: Focus on Ferroptosis

Journal of Medicinal Chemistry
Ferroptosis is a nonapoptotic form of cell death discovered in 2012. Noninvasive treatments regulating ferroptosis are important for a wide range of diseases. Among the noninvasive treatments, sonodynamic therapy (SDT) has become promising due to its strong tissue penetration and few side effects.
Wendi Su, Hao Wang, Juhong Pan, Qing Zhou   +3 more
openaire   +2 more sources

Sonodynamic Therapy Mediated by Emodin Induces the Oxidation of Microtubules to Facilitate the Sonodynamic Effect

Ultrasound in Medicine & Biology, 2018
In previous studies, sonodynamic therapy mediated by emodin (emodin-SDT) induced cytoskeletal filament disruption and apoptosis of THP-1-derived macrophages. In this research, we investigated the underlying mechanism. THP-1-derived macrophages were incubated with emodin and exposed to ultrasound irradiation. After emodin-SDT, we measured the production
Jili, Qian, Qianping, Gao
openaire   +2 more sources

Sonodynamic therapy for metastatic melanoma to the brain

Journal of Neuro-Oncology, 2021
Darrah Sheehan, Kimball Sheehan, Jason Sheehan   +2 more
openaire   +2 more sources

Sonodynamic and chemodynamic therapy based on organic/organometallic sensitizers

Coordination Chemistry Reviews, 2021
Yin Jun, Shenghua Liu, Juyoung Yoon
exaly  

Sonodynamic Therapy

Resonance
Rajesh Kushwaha, Samya Banerjee
openaire   +3 more sources

Design and Challenges of Sonodynamic Therapy System for Cancer Theranostics: From Equipment to Sensitizers

Advanced Science, 2021
Zhifei Dai, Zhifei Dai, Zhuoran Gong
exaly  

Ultrasound-driven sonodynamic therapy for hepatocellular carcinoma

Chemical Communications
The mechanism of SDT in the treatment of hepatocellular carcinoma (HCC) mainly involves the regulation of reactive oxygen species (ROS) levels and the induction of multiple modes of cell death.
Wenhui Chen, Lile Dong, Xiulin Xiao
openaire   +2 more sources

Investigation of the mechanisms of sonodynamic therapy

There is a pressing need to develop novel platform cancer therapeutics that are efficient, reduce side effects, and are minimally invasive. One emerging platform is photodynamic therapy where light is used as an external stimulus to activate drugs at a target location, however, clinical applications are limited due to poor light penetration. Previously,
Singh, Kritika, Oppermann, Udo
openaire   +2 more sources

Macrophage-Targeted Sonodynamic/Photothermal Synergistic Therapy for Preventing Atherosclerotic Plaque Progression Using CuS/TiO2 Heterostructured Nanosheets

ACS Nano, 2022
Yue Pan, Zhengyu Cao
exaly