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Combinations with Sonodynamic Therapy

2023
Like photodynamic therapy, sonodynamic therapy is based on ultrasonic activation of a sonodynamic therapy sensitizer to kill disease cells by production of reactive oxygen species in excess of what can be handled by cellular redox homeostasis biochemical pathways.
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The promise of sonodynamic therapy

Cancer and Metastasis Reviews, 2013
Sonodynamic therapy is a potential cancer treatment modality that has been gaining support due to its effectiveness in both in vitro and in vivo studies. The therapeutic method combines ultrasonic irradiation with drugs known as sonosensitizers that amplify its ability to inflict preferential damage on malignant cells.
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Recent developments of sonodynamic therapy in antibacterial application

Nanoscale, 2022
This review summarizes the currently available sonosensitizers for antibacterial SDT and digs into innovative biotechnologies to improve SDT efficiency.
Ruhao Wang   +6 more
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Sonodynamic therapy: A potential treatment for atherosclerosis

Life Sciences, 2018
Atherosclerosis (AS), a chronic arterial disease, is one of the major causes of morbidity and mortality worldwide. Several treatment modalities have been demonstrated to be effective in treating AS; however, the mortality rate due to AS remains high. Sonodynamic therapy (SDT) is a promising new treatment using low-intensity ultrasound in combination ...
Chi, Geng   +8 more
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Inorganic Sonosensitizers for Sonodynamic Therapy in Cancer Treatment

Small, 2023
AbstractThe rapid development of nanomedicine and nanobiotechnology has allowed the emergence of various therapeutic modalities with excellent therapeutic efficiency and biosafety, among which, the sonodynamic therapy (SDT), a combination of low‐intensity ultrasound and sonosensitizers, is emerging as a promising noninvasive treatment modality for ...
Xianshuo Cao   +5 more
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Recent Developments of Inorganic Nanosensitizers for Sonodynamic Therapy

Advanced Healthcare Materials, 2023
AbstractAs a noninvasive treatment, sonodynamic therapy (SDT) has been widely used in the treatment of tumors because of its ability to penetrate deep tissue with few side effects. As the key factor of SDT, it is meaningful to design and synthesize efficient sonosensitizers. Compared with organic sonosensitizers, inorganic sonosensitizers can be easily
Zongyan He   +3 more
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The promising interplay between sonodynamic therapy and nanomedicine

Advanced Drug Delivery Reviews, 2022
Sonodynamic therapy (SDT) is a non-invasive approach for cancer treatment in which chemical compounds, named sonosensitizers, are activated by non-thermal ultrasound (US), able to deeply penetrate into the tissues. Despite increasing interest, the underlying mechanisms by which US triggers the sonosensitizer therapeutic activity are not yet clearly ...
Roberto Canaparo   +3 more
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Probing the mechanisms of sonodynamic therapy

The Journal of the Acoustical Society of America, 2022
Drugs that can be activated by a physical stimulus at a target site offer great potential for limiting toxic side effects, e.g., in cancer therapy. In photodynamic therapy, light is used as the stimulus, but clinical applications are limited due to the poor penetration of light in tissue.
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Advances in Sonodynamic Therapy: Focus on Ferroptosis

Journal of Medicinal Chemistry
Ferroptosis is a nonapoptotic form of cell death discovered in 2012. Noninvasive treatments regulating ferroptosis are important for a wide range of diseases. Among the noninvasive treatments, sonodynamic therapy (SDT) has become promising due to its strong tissue penetration and few side effects.
Wendi Su   +3 more
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Electronic band structure modulation for sonodynamic therapy

Journal of Materials Chemistry B
The common ways and various materials used for modulating electronic band structure for SDT are summarized.
Yafang Shi   +10 more
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