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Metal Complexes for Cancer Sonodynamic Therapy

ChemBioChem, 2022
AbstractSonodynamic therapy (SDT) for cancer treatment is gaining attention owing to its non‐invasive property and ultrasound‘s (US) deep tissue penetration ability. In SDT, US activates the sonosensitizer at the target deep‐seated tumors to generate reactive oxygen species (ROS), which ultimately damage tumors.
Arif Ali Mandal   +3 more
openaire   +2 more sources

Advanced biotechnology-assisted precise sonodynamic therapy

Chemical Society Reviews, 2021
Herein, we provide the enhancement of SDT effect through elaborate strategies including the design and modification of sonosensitizers, the combination other therapy modalities, and molecular imaging-guided SDT for precise treatment.
Yi Zhang   +9 more
openaire   +2 more sources

Stimuli responsive nanosonosensitizers for sonodynamic therapy

Journal of Controlled Release, 2023
Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth, high spatiotemporal selectivity, and noninvasive therapeutic method.
Zeyu, Jiang, Wenjing, Xiao, Qinrui, Fu
openaire   +2 more sources

Sonodynamic therapy

Ultrasonics, 2008
Recently, there have been numerous reports on the application of non-thermal ultrasound energy for treating various diseases in combination with drugs. Furthermore, the introduction of microbubbles and nanobubbles as carriers/enhancers of drugs has added a whole new dimension to therapeutic ultrasound.
Katsuro, Tachibana   +2 more
openaire   +2 more sources

SONODYNAMIC THERAPY (SDT) AND GENE THERAPY

CARDIOMETRY, 2023
One in Four Deaths in Japan Caused by Cancer. Cancer is the most common cause of death for Japanese people who are 40 and over, while suicide is the leading cause among young people.
openaire   +1 more source

Studies On Sonodynamic Cancer Therapy

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1992
Chemical agents such as hematoporphyrin have been found to have a sonochemical activity to induce anti-tumor effects. The same kind of sonochemical reactions producing active oxygen species has been demonstrated to be localized with a highly focused ultrasound in a specially developed tissue-mimicking phantom.
null Umemura   +4 more
openaire   +2 more sources

Free Radical Intermediates in Sonodynamic Therapy

Annals of the New York Academy of Sciences, 2000
Abstract: Current understanding of the mechanism of sonodynamic action (i.e. the ultrasound‐dependent enhancement of the cytotoxic action of certain drugs ‐ sonosensitizers) with potential applications for cancer therapy is presented. The experimental evidence suggests that sonosensitization is due to the chemical activation of sonosensitizers inside ...
V, Misík, P, Riesz
openaire   +2 more sources

Sonochemistry of sonodynamic therapy

The Journal of the Acoustical Society of America, 1998
Sonodynamic therapy is a promising modality for cancer treatment based on the synergistic effect of cell killing by a combination of drugs (sonosensitizers) and ultrasound. The effectiveness of sonodynamic therapy was demonstrated in cell studies and in tumor-bearing animals.
Peter Riesz, Vladimir Misik
openaire   +1 more source

Ultrasound Dose Fractionation in Sonodynamic Therapy

Ultrasound in Medicine & Biology, 2010
Sonodynamic therapy (SDT) is a new modality in cancer therapy and it is based on preferential uptake and/or retention of a sonosensitizing drug in tumor tissues and subsequent activation of the drug by ultrasound. The dose fractionation effect in radiation therapy has been known for more than a century, but it is not reported in SDT so far.
Amir H, Barati, Manijeh, Mokhtari-Dizaji
openaire   +2 more sources

Tumor Microenvironment‐Related Sonodynamic Therapy Mediates Tumor Therapy

Advanced Therapeutics, 2023
AbstractSonodynamic therapy (SDT) is a rapidly developing, safe, and noninvasive method for tumor treatment. SDT relies on ultrasound to stimulate the activity of sonosensitizers, induce the production of many reactive oxygen species (ROS), and mediate tumor cell death.
Xiaodong Wang   +4 more
openaire   +1 more source

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