Results 41 to 50 of about 2,350,497 (231)

Photo-sonodynamic combination activity of cationic morpholino-phthalocyanines conjugated to nitrogen and nitrogen-sulfur doped graphene quantum dots against MCF-7 breast cancer cell line in vitro [PDF]

, 2021
In this work, we explore the reactive oxygen species (ROS) generation abilities of cationic morpholino-substituted-phthalocyanine (Pc) conjugated to nitrogen (NGQDs) and nitrogen-sulfur (NSGQDs) doped-graphene quantum dots upon irradiation with light for
Nyokong, Tebello, Nene, Lindokhule Cindy
core   +1 more source

Sonodynamic Therapy Suppresses Neovascularization in Atherosclerotic Plaques via Macrophage Apoptosis-Induced Endothelial Cell Apoptosis

JACC: Basic to Translational Science, 2020
Summary: During atherosclerosis plaque progression, pathological intraplaque angiogenesis leads to plaque rupture accompanied by thrombosis, which is probably the most important cause of arteries complications such as cerebral and myocardial infarction ...
Jianting Yao, MD, PhD, Weiwei Gao, MD, Yu Wang, MD, PhD, Lu Wang, PhD, Kamal Diabakte, MD, Jinyang Li, MD, Jiemei Yang, MD, Yongxing Jiang, MD, Yuerong Liu, MD, Shuyuan Guo, MD, Xuezhu Zhao, MD, Zhengyu Cao, MD, Xi Chen, MD, PhD, Qiannan Li, MD, Haiyu Zhang, PhD, Wei Wang, MD, Zhen Tian, PhD, Bicheng Li, MD, PhD, Fang Tian, MD, PhD, Guodong Wu, MD, Shirin Pourteymour, PhD, Xi Huang, MD, Fancheng Tan, MD, Xiaoru Cao, MD, Zhuowen Yang, MD, Kang Li, PhD, Yan Zhang, PhD, Yong Li, MD, PhD, Zhiguo Zhang, PhD, Hong Jin, MD, PhD, Ye Tian, MD, PhD   +30 more
doaj   +1 more source

Multiple stimuli-responsive nanosystem for potent, ROS-amplifying, chemo-sonodynamic antitumor therapy

Bioactive Materials, 2022
Although sonodynamic therapy (SDT) is a promising non-invasive tumor treatment strategy due to its safety, tissue penetration depth and low cost, the hypoxic tumor microenvironment limits its therapeutic effects. Herein, we have designed and developed an
JunJie Tang, Xiaoge Zhang, Lili Cheng, Yadong Liu, You Chen, Zhaozhong Jiang, Jie Liu   +6 more
doaj   +1 more source

Application of metalloporphyrin sensitizers for the treatment or diagnosis of tumors

Journal of Chemical Research, 2022
At present, metalloporphyrin compounds demonstrate three main uses as anticancer sensitizers: (1) photosensitizers, (2) photothermal conversion agents, and (3) ultrasound sensitizers.
Hongyu Luo, Wenmei Yu, Si Chen, Zhenyu Wang, Zejie Tian, Jun He, Yunmei Liu   +6 more
doaj   +1 more source

Multifaceted nanozymes for synergistic antitumor therapy: A review

Materials & Design, 2022
Although various cancer therapies have been developed in the last decade, much of their anti-tumor effects are restricted by the tumor microenvironment complexity, such as the hypoxia in photodynamic therapy and sonodynamic therapy, and the poor ...
Qing Li, Tingting Wu, Xiaowan Fan, Xiaobo Guo, Wei Jiang, Kelong Fan   +5 more
doaj   +1 more source

Mucus-Permeable Sonodynamic Therapy Mediated Amphotericin B-Loaded PEGylated PLGA Nanoparticles Enable Eradication of Candida albicans Biofilm

, 2023
Min Yang,1,2 Mengyao Xie,1,2 Jiajun Guo,1,2 Yuqing Zhang,1,2 Yan Qiu,1,2 Zhibiao Wang,1,2 Yonghong Du1,2 1State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016 ...
Qiu Y, Guo J, Zhang Y, Yang M, Xie M, Du Y, Wang Z   +6 more
core  

Magnetically actuated sonodynamic nanorobot collectives for potentiated ovarian cancer therapy

Frontiers in Bioengineering and Biotechnology
Ovarian cancer presents a substantial challenge due to its high mortality and recurrence rates among gynecological tumors. Existing clinical chemotherapy treatments are notably limited by drug resistance and systemic toxic side effects caused by off ...
Yixuan Zhou, Yixuan Zhou, Ziqi Cao, Lixian Jiang, Ying Chen, Xiaoyu Cui, Jianrong Wu, Xue Xie, Longchen Wang, Tao Ying, Tao Ying   +10 more
doaj   +1 more source

Cavitation assisted endoplasmic reticulum targeted sonodynamic droplets to enhanced anti-PD-L1 immunotherapy in pancreatic cancer

Journal of Nanobiotechnology, 2022
Background Sonodynamic therapy (SDT) induces immunogenic cell death (ICD) in tumors and promises to play an assistive role in immunotherapy in pancreatic cancer. However, the short half-life and limited diffusion distance of reactive oxygen species (ROS)
Jifan Chen, Liting Feng, Peile Jin, Jiaxin Shen, Jiayue Lu, Yue Song, Guowei Wang, Qin Chen, Deyi Huang, Ying Zhang, Chao Zhang, Youfeng Xu, Pintong Huang   +12 more
doaj   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source

Sonodynamic therapy in GBM treatment: state of the art and future directions

, 2022
evaluate the state of the art about sonodynamic therapy in GBM ...
Kevin giardina, Lapo Bonosi, Sofia musso, Umberto Emanuele benigno   +3 more
core   +1 more source