Results 51 to 60 of about 6,769 (222)

Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting [PDF]

, 2023
Diffuse Intrinsic Pontine Glioma (DIPG), now known as Diffuse Midline Glioma (DMG) is a devastating pediatric brain tumor with limited treatment options and a very poor prognosis.
Hynynen, Kullervo, LeBlang, Suzanne, Mueller, Sabine, Nazarian, Javad, Parekh, Kavya, Powlovich, Lauren, Zacharoulis, Stergios   +6 more
core   +1 more source

Intracellular Reactive Oxygen Species Generation Induced by High‐Frequency Ultrasound in Thickness Vibration Mode

Advanced Science, EarlyView.
Cell‐sized high‐frequency ultrasound using a lithium niobate transducer, previously ignored in reactive oxygen species (ROS) production, generated intracellular ROS at frequencies higher than conventionally used. The intracellular generation of ROS by cell‐sized high‐frequency ultrasound revealed in this study is expected to be applied to innovative ...
Kotaro Fujishiro, Satoshi Okada, Filippo Rossi, Takahiro Kuchimaru, Yuta Kurashina   +4 more
wiley   +1 more source

Sonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor

Scientific Reports, 2020
This article presents the construction of a multimodality platform that can be used for efficient destruction of brain tumor by a combination of photodynamic and sonodynamic therapy.
Ballav M. Borah, Joseph Cacaccio, Farukh A. Durrani, Wiam Bshara, Steven G. Turowski, Joseph A. Spernyak, Ravindra K. Pandey   +6 more
doaj   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer [PDF]

, 2018
At present, ultrasound radiation is broadly employed in medicine for both diagnostic and therapeutic purposes at various frequencies and intensities.
Limongi, T.
core   +4 more sources

Overcoming breast cancer cell treatment resistance by optimizing sonodynamic therapy and radiation sensitizers on lncRNA PVT1 and miR-1204 expression

Photodiagnosis and Photodynamic Therapy
Background: Acoustic cavitation is a foundational mechanism in ultrasound therapy, primarily through inertial cavitation resulting from microbubble collapse.
Ali Neshastehriz, Zeinab Hormozi-Moghaddam, Zahra Abedi Kichi, Seyedeh Mona Taheri, Seyed Mohammad Amini, Amir Aghaei   +5 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

5-Aminolevulinic Acid Triggered by Ultrasound Halts Tumor Proliferation in a Syngeneic Model of Breast Cancer

Pharmaceuticals, 2021
Sonodynamic therapy is a bimodal therapeutic approach in which a chemical compound and ultrasound (US) synergistically act to elicit oxidative damage, triggering cancer cell death.
Federica Foglietta, Giulia Gola, Elena Biasibetti, Maria Teresa Capucchio, Iside Bruni, Andrea Francovich, Gianni Durando, Loredana Serpe, Roberto Canaparo   +8 more
doaj   +1 more source

Development and characterisation of disulfiram-loaded PLGA nanoparticles for the treatment of non-small cell lung cancer [PDF]

, 2017
Non-Small Cell Lung Cancer (NSCLC) is the most common type of lung cancer in both men and women. A recent phase IIb study demonstrated that disulfiram (DSF) in combination with cisplatin and vinorelbine was well tolerated and prolonged the survival of ...
Ahmed, Zahima, Iqbal, Mohammed, McConville, Christopher, Najlah, Mohammad, Tawari, Patrica, Wang, Weiguang, Wang, Zhipeng   +6 more
core   +2 more sources

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source