Results 51 to 60 of about 2,350,497 (231)

Overcoming breast cancer cell treatment resistance by optimizing sonodynamic therapy and radiation sensitizers on lncRNA PVT1 and miR-1204 expression

Photodiagnosis and Photodynamic Therapy
Background: Acoustic cavitation is a foundational mechanism in ultrasound therapy, primarily through inertial cavitation resulting from microbubble collapse.
Ali Neshastehriz, Zeinab Hormozi-Moghaddam, Zahra Abedi Kichi, Seyedeh Mona Taheri, Seyed Mohammad Amini, Amir Aghaei   +5 more
doaj   +1 more source

Single Atom‐Doped Nanosonosensitizers for Mutually Optimized Sono/Chemo‐Nanodynamic Therapy of Triple Negative Breast Cancer

Advanced Science, 2023
Sonodynamic therapy (SDT) represents a promising therapeutic modality for treating breast cancer, which relies on the generation of abundant reactive oxygen species (ROS) to induce oxidative stress damage.
Qiqing Chen, Min Zhang, Hui Huang, Caihong Dong, Xinyue Dai, Guiying Feng, Ling Lin, Dandan Sun, Dayan Yang, Lin Xie, Yu Chen, Jia Guo, Xiangxiang Jing   +12 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Sonodynamic therapy using water-dispersed TiO2-polyethylene glycol compound on glioma cells : Comparison of cytotoxic mechanism with photodynamic therapy [PDF]

, 2011
Sonodynamic therapy is expected to be a novel therapeutic strategy for malignant gliomas. The titanium dioxide (TiO2) nanoparticle, a photosensitizer, can be activated by ultrasound. In this study, by using water-dispersed TiO2 nanoparticles, an in vitro
Kanehira, Koki, Terasaka, Shunsuke, Koki Kanehira, Yamaguchi, Shigeru, Kobayashi, Hiroyuki, Hiroyuki Kobayashi, Houkin, Kiyohiro, Shigeru Yamaguchi, Takuhito Narita, Nobuki Kudo, Sonezaki, Shuji, Kubota, Yoshinobu, Kudo, Nobuki, Shunsuke Terasaka, Shuji Sonezaki, Yoshinobu Kubota, Narita, Takuhito, Kiyohiro Houkin   +17 more
core   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Glycosylated Porphyrin Derivatives for Sonodynamic Therapy: ROS Generation and Cytotoxicity Studies in Breast Cancer Cells

, 2023
Sonodynamic therapy (SDT) is a promising alternative to photodynamic therapy for achieving site-specific cytotoxic therapy. Porphyrin derivative molecules have been reported extensively in photodynamic therapy.
Vijayalakshmi Pandey (8797151), Kuldeep Jajoria (17711054), Himanshu Shekhar (4031597), Manita Das (6940607), Dhiraj Bhatia (9407165), Iti Gupta (8797154)   +5 more
core   +1 more source

Ultrasound targeted microbubble destruction using docetaxel and Rose Bengal loaded Microbubbles for targeted Chemo-Sonodynamic therapy treatment of prostate cancer [PDF]

, 2023
Docetaxel (DTX) chemotherapy is commonly used in the treatment of patients with advanced prostate cancer demonstrating modest improvements in survival. As these patients are often elderly and the chemotherapy treatment is not targeted, it is often poorly
Bridgeen Callan, Stephanie McKeown, Callan, Bridgeen, McKeown, Stephanie, O'Sullivan, Joe M, Declan O'Rourke, Nesbitt, Heather, Paul Kelly, O'Rourke, Declan, John F. Callan, O'Sullivan, Joe M; id_orcid, Thomas McKaig, Heather Nesbitt, Logan, Keiran, Callan, John F, Anthony P. McHale, McHale, Anthony P, Kelly, Paul, Keiran Logan, Joe M. O'Sullivan, McKaig, Thomas   +20 more
core   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

Angewandte Chemie, EarlyView.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu, Liping Zhang, Ziwei Wang, Yachao Wang, Gelin Xu, Feng Chi, Dongxia Zhu, Martin R. Bryce, Ben Zhong Tang, Lijie Ren   +9 more
wiley   +2 more sources

Sonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor

Scientific Reports, 2020
This article presents the construction of a multimodality platform that can be used for efficient destruction of brain tumor by a combination of photodynamic and sonodynamic therapy.
Ballav M. Borah, Joseph Cacaccio, Farukh A. Durrani, Wiam Bshara, Steven G. Turowski, Joseph A. Spernyak, Ravindra K. Pandey   +6 more
doaj   +1 more source

Development and Optimisation of in vitro Sonodynamic Therapy for Glioblastoma

Scientific Reports, 2023
Abstract Background Sonodynamic therapy (SDT) is currently on critical path for glioblastoma therapeutics. However, the molecular mechanisms underlying the therapeutic functions of SDT remain enigmatic due to the lack of intricately optimised instrumentation capable of modulating SDT delivery in ...
Keenlyside, Andrew, Marples, Theodore, Gao, Zifan, Hu, Hong, Nicely, Lynden Guy, Nogales, Joaquina, Li, Han, Landgraf, Lisa, Solth, Anna, Melzer, Andreas, Hossain-Ibrahim, Kismet, Huang, Zhihong, Banerjee, Sourav, Joseph, James   +13 more
openaire   +5 more sources