Results 61 to 70 of about 6,769 (222)

Sonodynamic therapy with photosensitizers and its combination with photodynamic therapy in treatment of malignant tumors

Biomedical Photonics, 2014
The article reviews mechanisms of sonodynamic therapy with photosensitizers (ultrasound + photosensitizer) and combination of sonodynamic with photodynamic therapy (ultrasound + photosensitizer + light exposure) for treatment of malignant tumors ...
D. A. Zerkovskiy, E. N. Alexandrova, T. P. Laptsevich, Ju. P. Istomin   +3 more
doaj   +2 more sources

Biomimetic Metal-Organic Framework Nanoparticles for Synergistic Combining of SDT-Chemotherapy Induce Pyroptosis in Gastric Cancer

Frontiers in Bioengineering and Biotechnology, 2022
In recent years, sonodynamic therapy (SDT) has been widely developed for cancer research as a promising non-invasive therapeutic strategy. Here, we synthesized zeolitic imidazole frameworks-8 (ZIF-8) and utilized its properties to encapsulate hydrophobic
Zhu Yu, Zhu Yu, Wenlong Cao, Wenlong Cao, Chuangye Han, Zhen Wang, Zhen Wang, Yue Qiu, Yue Qiu, Jiancheng Wang, Jiancheng Wang, Mengda Wei, Mengda Wei, Junfu Wang, Junfu Wang, Siwen Zhang, Siwen Zhang, Senfeng Liu, Shutian Mo, Junqiang Chen, Junqiang Chen   +20 more
doaj   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Research progress of glucose oxidase-mediated multimodal cancer therapy

上海师范大学学报. 自然科学版, 2021
This article briefly introduces the application of glucose oxidase(GOx) in cancer treatment research, including monotherapy(starvation therapy(ST), oxidation therapy), bimodal therapy(synergistic chemotherapy(CT), chemical dynamic therapy(CDT ...
CAO Yushi, YANG Hong
doaj   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Research progress in sonodynamic therapy

上海师范大学学报. 自然科学版, 2020
Sonodynamic therapy(SDT)works by the synergistic effect of ultrasound and sonosensitizers to kill cancer cells through multiple mechanisms.As a mechanical wave, ultrasound can penetrate deep tissues.Compared with traditional treatment methods, SDT uses ...
LAI Kexin, TIAN Ya, WU Huixia
doaj   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Sonodynamic therapy-based nanoplatforms for combating bacterial infections

Ultrasonics Sonochemistry, 2023
The rapid spread and uncontrollable evolution of antibiotic-resistant bacteria have already become urgent global to treat bacterial infections. Sonodynamic therapy (SDT), a noninvasive and effective therapeutic strategy, has broadened the way toward dealing with antibiotic-resistant bacteria and biofilms, which base on ultrasound (US) with ...
Pei-Yao Xu, Ranjith Kumar Kankala, Shi-Bin Wang, Ai-Zheng Chen   +3 more
openaire   +3 more sources

Investigation into the Sonodynamic Activity of Three Newly Synthesized Derivatives of Ciprofloxacin

Molecules
Sonosensitizers play a crucial role in the efficacy of sonodynamic antitumor therapy (SDT) and sonodynamic antimicrobial chemotherapy (SACT), highlighting the necessity for the development of new compounds with good sonodynamic activity.
Ying Zheng, Jing Lv, Jun Zhang, Yu Liu, Xiaofang Wang, Bin Liu   +5 more
doaj   +1 more source