Results 81 to 90 of about 6,769 (222)

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Application and Challenge of Metalloporphyrin Sensitizers in Noninvasive Dynamic Tumor Therapy

Molecules
Dynamic tumor therapies (mainly including photodynamic therapy (PDT) and sonodynamic therapy (SDT)) offer new approaches to cancer treatment. They are often characterized by their noninvasive nature, high selectivity, and low toxicity.
Jiacheng Ouyang, Dan Li, Lizhen Zhu, Xiaoyuan Cai, Lanlan Liu, Hong Pan, Aiqing Ma   +6 more
doaj   +1 more source

The abscopal effects of sonodynamic therapy in cancer [PDF]

The abscopal effect is a phenomenon wherein localised therapy on the primary tumour leads to regression of distal metastatic growths. Interestingly, various pre-clinical studies utilising sonodynamic therapy (SDT) have reported significant abscopal ...
Banerjee, Sourav, Collins, Victoria G., Hossain-Ibrahim, Kismet, Hutton, Dana, Joseph, James   +4 more
core   +5 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Interfacial Chemistry‐Tailored Silica&Metal‐Based Heterostructures: from Rational Design to Antibacterial Applications

Small, EarlyView.
This review explores how interfacial engineering of silica&metal‐based nanohybrids enables precise architectural control, leveraging the structural and functional contributions of silica to overcome the inherent limitations of meta‐based materials. The antibacterial performance of these nanohybrids including membrane disruption, stimuli‐responsive ...
Dan Cheng, Yuchao Gu, Chengzhong Yu
wiley   +1 more source

Recent advances of sonodynamic therapy in cancer treatment

Cancer Biology & Medicine, 2016
Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid ...
Guo-Yun Wan, Guo-Yun Wan, Yang Liu, Bo-Wei Chen, Yuan-Yuan Liu, Yin-Song Wang, Ning Zhang, Yang Liu, Bo-Wei Chen, Yuan-Yuan Liu, Yin-Song Wang, Ning Zhang   +11 more
openaire   +4 more sources

External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications

Small, EarlyView.
Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko, Jungsue Choi, Hyeonjeong Noh, Sohyeon Seo, Heedong Kwon, Seungjune Lee, Hyoyoung Lee   +6 more
wiley   +1 more source

Development of giant liposomal formulation for drug delivery and tissue engineering application [PDF]

, 2013
This thesis delineates the development of giant liposomal formulation and application of drug loaded giant liposome encapsulated hydrogel as a theranostics formulation.
Choudhury, Binapani
core  

Targeted Chemo-Sonodynamic Therapy Treatment of Breast Tumours Using Ultrasound Responsive Microbubbles Loaded with Paclitaxel, Doxorubicin and Rose Bengal. [PDF]

, 2019
Mastectomy is a common surgical treatment used in the management of breast cancer but has associated physical and psychological consequences for the patient.
Callan, Bridgeen, Callan, J, Foglietta, Federica, Gao, Jinhui, Kamila, Sukanta, Logan, Keiran, McHale, Anthony P., McKaig, Thomas, Nesbitt, Heather, Nomikou, Nikolitsa, Sheng, Yingjie   +10 more
core   +2 more sources