Results 51 to 60 of about 3,188 (200)

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

Advanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu, Yu Yang, Rui Zhao, Linwei Huang, Xingyu Qi, Min Wu, Jianliang Shen   +6 more
wiley   +1 more source

Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer

Journal of Nanobiotechnology, 2021
Background Colorectal cancer is known to be resistant to immune checkpoint blockade (ICB) therapy. Sonodynamic therapy (SDT) has been reported to improve the efficacy of immunotherapy by inducing immunogenic cell death (ICD) of cancer.
Guoyun Wan, Xuheng Chen, Haijiao Wang, Shenglei Hou, Qian Wang, Yuanyuan Cheng, Qian Chen, Yingge Lv, Hongli Chen, Qiqing Zhang   +9 more
doaj   +1 more source

Artesunate Enhances the Cytotoxicity of 5-Aminolevulinic Acid-Based Sonodynamic Therapy against Mouse Mammary Tumor Cells In Vitro [PDF]

, 2021
Sonodynamic therapy (SDT) kills tumor cells through the synergistic effects of ultrasound (US) and a sonosensitizer agent. 5-Aminolevulinic acid (5-ALA) has been used as a sonodynamic sensitizer for cancer treatment.
Azuma, Kazuo, Imagawa, Tomohiro, Ishizuka, Masahiro, Itoh, Norihiko, Kurahashi, Tsukasa, Murahata, Yusuke, Okamoto, Yoshiharu, Osaki, Tomohiro, Tanaka, Tohru, Tsuka, Takeshi, Uto, Yoshihiro, Yamanaka, Nobuyasu   +11 more
core  

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Mitochondria-Targeted Mesoporous Titanium Dioxide Nanoplatform for Synergistic Nitric Oxide Gas-Sonodynamic Therapy of Breast Cancer

International Journal of Nanomedicine, 2022
Shuting Zuo, Yan Zhang, Zhenyu Wang, Jing Wang Department of Breast Surgery, The Second Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jing Wang, Department of Breast Surgery, The Second Hospital of Jilin University ...
Zuo S, Zhang Y, Wang Z, Wang J
doaj  

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Sonodynamic therapy for breast cancer: A literature review

Open Chemistry, 2022
Breast cancer (BC) is a malignant tumor with the highest incidence among women. Surgery, radiotherapy, and chemotherapy are currently used as the first-line methods for treating BC.
Zhou Hai-ying, Chen Yi, Li Ping, He Xiaoxin, Zhong Jieyu, Hu Zhengming, Liu Li, Chen Yun, Cui Guanghui, Sun Desheng, Zheng Tingting   +10 more
doaj   +1 more source

Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting [PDF]

, 2023
Diffuse Intrinsic Pontine Glioma (DIPG), now known as Diffuse Midline Glioma (DMG) is a devastating pediatric brain tumor with limited treatment options and a very poor prognosis.
Hynynen, Kullervo, LeBlang, Suzanne, Mueller, Sabine, Nazarian, Javad, Parekh, Kavya, Powlovich, Lauren, Zacharoulis, Stergios   +6 more
core   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source