Results 71 to 80 of about 3,319 (195)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Update of Photodynamic Therapy and Sonodynamic Therapy in Treating Rheumatoid Arthritis [PDF]

Advanced Ultrasound in Diagnosis and Therapy
Rheumatoid arthritis (RA) stands as a prevalent chronic autoimmune condition globally. Although conventional disease-modifying antirheumatic drugs (DMARDs) offer relief from systemic inflammation, they frequently entail undesirable side effects ...
Zhao Chenyang, Sun Desheng, Tan Li, Chen Xiangmei
doaj   +1 more source

Nanomaterials-based precision sonodynamic therapy enhancing immune checkpoint blockade: A promising strategy targeting solid tumor

Materials Today Bio, 2023
Burgeoning is an evolution from conventional photodynamic therapy (PDT). Thus, sonodynamic therapy (SDT) regulated by nanoparticles (NPs) possesses multiple advantages, including stronger penetration ability, better biological safety, and not reactive ...
Xinlun Dai, Yangyang Du, Yumei Li, Fei Yan   +3 more
doaj   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Functional Evaluation of TiO_2 Nanoparticles-Incorporated Polyion Complex Micelles for Sonodynamic Therapy [PDF]

, 2018
Osaka Prefecture University (大阪府立大学)博士（工学）application/pdf学位記番号：論工第1522号, 指導教員：八木　繁幸doctoral ...
山本, 聡
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Precise Design of TiO2@CoOx Heterostructure via Atomic Layer Deposition for Synergistic Sono‐Chemodynamic Oncotherapy

Advanced Science
Sonodynamic therapy (SDT), a tumor treatment modality with high tissue penetration and low side effects, is able to selectively kill tumor cells by producing cytotoxic reactive oxygen species (ROS) with ultrasound‐triggered sonosensitizers.
Wen Liu, Runrun Shao, Lingyun Guo, Jianliang Man, Chengwu Zhang, Lihong Li, Haojiang Wang, Bin Wang, Lixia Guo, Sufang Ma, Bin Zhang, Haipeng Diao, Yong Qin, Lili Yan   +13 more
doaj   +1 more source

Biomimetic amorphous titania nanoparticles as ultrasound responding agents to improve cavitation and ros production for sonodynamic therapy [PDF]

, 2020
Conventional therapies to treat cancer often exhibit low specificity, reducing the efficiency of the treatment and promoting strong side effects.
Cauda V., Goncalves M. C., Laurenti M., Matos J. C., Pereira L. C. J., Vighetto V., Waerenborgh J. C.   +6 more
core   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications

Small, EarlyView.
Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko, Jungsue Choi, Hyeonjeong Noh, Sohyeon Seo, Heedong Kwon, Seungjune Lee, Hyoyoung Lee   +6 more
wiley   +1 more source