Results 51 to 60 of about 3,319 (195)

Targeted Chemo-Sonodynamic Therapy Treatment of Breast Tumours Using Ultrasound Responsive Microbubbles Loaded with Paclitaxel, Doxorubicin and Rose Bengal. [PDF]

, 2019
Mastectomy is a common surgical treatment used in the management of breast cancer but has associated physical and psychological consequences for the patient.
Callan, Bridgeen, Callan, J, Foglietta, Federica, Gao, Jinhui, Kamila, Sukanta, Logan, Keiran, McHale, Anthony P., McKaig, Thomas, Nesbitt, Heather, Nomikou, Nikolitsa, Sheng, Yingjie   +10 more
core   +2 more sources

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Sonodynamic inactivation of Gram-positive and Gram-negativebacteria using a Rose Bengal–antimicrobial peptide conjugate [PDF]

, 2017
Combating antimicrobial resistance is one of the most serious public health challenges facing society today. The development of new antibiotics or alternative techniques that can help combat antimicrobial resistance is being prioritised by many ...
Callan, John F, Costley, David, Dooley, James, Hamblin, Michale R, Huang, Ying-Ying, McHale, Anthony P, Nesbitt, Heather, Ternan, Nigel   +7 more
core   +2 more sources

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Sonodynamic therapy for breast cancer: A literature review

Open Chemistry, 2022
Breast cancer (BC) is a malignant tumor with the highest incidence among women. Surgery, radiotherapy, and chemotherapy are currently used as the first-line methods for treating BC.
Zhou Hai-ying, Chen Yi, Li Ping, He Xiaoxin, Zhong Jieyu, Hu Zhengming, Liu Li, Chen Yun, Cui Guanghui, Sun Desheng, Zheng Tingting   +10 more
doaj   +1 more source

Development and optimisation of in vitro sonodynamic therapy for glioblastoma [PDF]

, 2023
Sonodynamic therapy (SDT) is currently on critical path for glioblastoma therapeutics. SDT is a non-invasive approach utilising focused ultrasound to activate photosensitisers like 5-ALA to impede tumour growth.
Banerjee, Sourav, Gao, Zifan, Hossain-Ibrahim, Kismet, Hu, Hong, Huang, Zhihong, Joseph, James, Keenlyside, Andrew, Landgraf, Lisa, Li, Han, Marples, Theodore, Melzer, Andreas, Nicely, Lynden Guy, Nogales, Joaquina, Solth, Anna   +13 more
core   +2 more sources

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Emerging Piezoelectric Sonosensitizer for ROS-Driven Sonodynamic Cancer Therapy

Inorganics
As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound and sonosensitizers ...
Guiyun Wang, Yanxia Qi, Zhuang Liu, Ruowei Wang   +3 more
doaj   +1 more source

Mitochondria-Targeted Mesoporous Titanium Dioxide Nanoplatform for Synergistic Nitric Oxide Gas-Sonodynamic Therapy of Breast Cancer

International Journal of Nanomedicine, 2022
Shuting Zuo, Yan Zhang, Zhenyu Wang, Jing Wang Department of Breast Surgery, The Second Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jing Wang, Department of Breast Surgery, The Second Hospital of Jilin University ...
Zuo S, Zhang Y, Wang Z, Wang J
doaj  

Artesunate Enhances the Cytotoxicity of 5-Aminolevulinic Acid-Based Sonodynamic Therapy against Mouse Mammary Tumor Cells In Vitro [PDF]

, 2021
Sonodynamic therapy (SDT) kills tumor cells through the synergistic effects of ultrasound (US) and a sonosensitizer agent. 5-Aminolevulinic acid (5-ALA) has been used as a sonodynamic sensitizer for cancer treatment.
Azuma, Kazuo, Imagawa, Tomohiro, Ishizuka, Masahiro, Itoh, Norihiko, Kurahashi, Tsukasa, Murahata, Yusuke, Okamoto, Yoshiharu, Osaki, Tomohiro, Tanaka, Tohru, Tsuka, Takeshi, Uto, Yoshihiro, Yamanaka, Nobuyasu   +11 more
core