Results 61 to 70 of about 3,319 (195)

Biomedical Applications of Reactive Oxygen Species Generation by Metal Nanoparticles [PDF]

, 2020
The design, synthesis and characterization of new nanomaterials represents one of the most dynamic and transversal aspects of nanotechnology applications in the biomedical field. New synthetic and engineering improvements allow the design of a wide range
Federica Foglietta, Loredana Serpe, Roberto Canaparo, Tania Limongi   +3 more
core   +2 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer

Journal of Nanobiotechnology, 2021
Background Colorectal cancer is known to be resistant to immune checkpoint blockade (ICB) therapy. Sonodynamic therapy (SDT) has been reported to improve the efficacy of immunotherapy by inducing immunogenic cell death (ICD) of cancer.
Guoyun Wan, Xuheng Chen, Haijiao Wang, Shenglei Hou, Qian Wang, Yuanyuan Cheng, Qian Chen, Yingge Lv, Hongli Chen, Qiqing Zhang   +9 more
doaj   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Hematoporphyrin monomethyl ether sonodynamic therapy (HMME-SDT) mitigates keloid scarring via the PI3K-AKT signaling pathway

Photodiagnosis and Photodynamic Therapy
This study investigates the effects and underlying molecular mechanisms of Hematoporphyrin Monomethyl Ether Sonodynamic Therapy (HMME-SDT) on keloid fibroblasts (KFs) in vitro and in vivo, utilizing animal models.The activation effect of ultrasound on HMME was ascertained using UV-visible light absorption spectroscopy.
Jingting Zhao, Zhiyi Xu, Min Li, Xiaoyu Zhai, Siqi Shen, Jing Wang, Zhinan Shi, Li Gu, Shu Zhou, Liqun Gu, Lin Chen, Bingrong Zhou, Hui Hua   +12 more
openaire   +3 more sources

Development of giant liposomal formulation for drug delivery and tissue engineering application [PDF]

, 2013
This thesis delineates the development of giant liposomal formulation and application of drug loaded giant liposome encapsulated hydrogel as a theranostics formulation.
Choudhury, Binapani
core  

Catalytically active NaNbO3 nanorods for sonodynamic cancer therapy

, 2023
Sonodynamic therapy (SDT) has received a lot of interest due to its deep tissue penetration and lack of invasiveness. However, SDT still prioritizes the creation of highly effective, multifunctional, and biocompatible sonosensitizers to improve the ...
Chang, Meiqi, Ding, Xinyi
core  

Correction to: Nanotechnology-augmented sonodynamic therapy and associated immune-mediated effects for the treatment of pancreatic ductal adenocarcinoma:Nanotechnology-augmented sonodynamic therapy and associated immune-mediated effects for the treatment of pancreatic ductal adenocarcinoma (Journal of Cancer Research and Clinical Oncology, (2023), 149, 8, (5007-5023), 10.1007/s00432-022-04418-y) [PDF]

, 2023
In Fig. 5 of this article, there were two errors in Fig. 5c, right panel. Firstly, the title of the graph (in the right panel) that had read “Target tumour” should have read “Off-target tumour”.
Callan, John F., Davidson, Brian, Farrell, Sian, Hadi, Marym Mohammad, Kubajewska, Ilona, MacRobert, Alexander J., Masood, Hamzah, McHale, Anthony P., Nesbitt, Heather, Ng, Alex, Nomikou, Nikolitsa, Patel, Shiv, Sciscione, Fabiola, Thomas, Keith   +13 more
core   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Enhancing SDT Efficacy of Doxorubicin‐Loaded Sonosensitizer Micelles to Overcome Resistance of Cancer Therapy by Optimizing Acoustic Parameters

Aggregate
Tumor drug resistance has been reported to be associated with drug efflux in tumor cells. Recently, a noninvasive and safe mechanism, sonodynamic therapy (SDT), has been proposed to be an oxidative stress strategy to potentially overcome drug efflux, but
Zhuoran Gong, Deshang Hou, Yunxue Xu, Mengxuan Wang, Shiyin Lin, Yingjuan Zheng, Zhifei Dai   +6 more
doaj   +1 more source