Results 51 to 60 of about 2,643 (179)

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Ca2+ sonotransfer into breast cancer cells in a suspension, 3-D spheroid and subcutaneous tumor models

Ultrasonics Sonochemistry
Calcium-based treatments have gained considerable attention in the field of electroporation, primarily, due to their comparable efficacy to conventional electro-chemotherapy.
Martynas Maciulevičius, Reda Rulinskaitė, Lukas Giedrimas, Rūta Palepšienė, Paulius Ruzgys, Rytis Jurkonis, Mindaugas Tamošiūnas, Renaldas Raišutis, Kristine Saleniece, Saulius Šatkauskas   +9 more
doaj   +1 more source

Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model

Frontiers in Oncology, 2021
The CD71+ erythroid progenitor cells (CECs) exhibit distinctive immunosuppressive properties and regulate antitumor immunity to enable tumor growth. We presented a novel and non-invasive approach to improving immunity by targeting the splenic CECs via ...
Xi Tan, Cuo Yi, Yi Zhang, Najiao Tang, Yali Xu, Zheng Liu   +5 more
doaj   +1 more source

Multiscale Acoustic Bubble Actuators Using Bioinspired Liquid‐Repellent Microstructures

Advanced Materials Technologies, Volume 11, Issue 8, 17 April 2026.
The article presents multiscale acoustic bubble actuators using bioinspired liquid‐repellent microstructures, enabling programmable trapping, pumping, mixing, and precise flow control. Mimicking springtail microstructures, these scalable actuators (200 µm–1 mm) offer multifunctionality in all‐in‐one devices, letter‐shaped arrays, and 3D cube ...
Cem Balda Dayan, Nima Mahkam, Nihal Olcay Dogan, Ville Liimatainen, Defne Hiz, Aleyna Ilgezdi, Daniel Razansky, Amirreza Aghakhani, Metin Sitti   +8 more
wiley   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Synthesis of echogenic liposomes for sonoporation

Micro & Nano Letters, 2022
Abstract Ultrasound contrast agents (UCAs), which are groups of engineered microbubbles, have been recently studied for drug delivery applications, since the cavitation of bubbles can increase the temporary permeability of nearby cells.
DongHee Park, Hyon Chel Jung, Juhyun Park, Seoku Bae, UnChul Shin, Suhng Wook Kim, Chul Woo Kim, Yong Heum Lee, Jongbum Seo   +8 more
openaire   +2 more sources

Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications

ChemistryEurope, Volume 4, Issue 4, April 2026.
Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari, Nicola Lomuscio, Fabio Bellina   +2 more
wiley   +1 more source

Immunosuppressive Microenvironment Reprogramming by Synergistic Sonodynamic Therapy of Phthalocyanine‐MOF Hybrids for Hepatocellular Carcinoma

Exploration, Volume 6, Issue 2, April 2026.
Hepatocellular carcinoma presents a formidable clinical challenge, constructing a hypoxic and immunosuppressive microenvironment that renders conventional therapies largely ineffective. In response, we have developed Pc@Zr‐MOF, a phthalocyanine‐integrated metal‐organic framework hybrid engineered to penetrate this defensive barrier.
Han Wu, Lihui Gu, Jiahao Xu, Chuyue Zhang, Mingda Wang, Chao Li, Lanqing Yao, Yongkang Diao, Yuchen Li, Fujie Chen, Huixuan Fan, Yuze Zhao, Feng Shen, Tian Yang   +13 more
wiley   +1 more source

Line tension of the pore edge in phospholipid/cholesterol bilayer from stretch molecular dynamics simulation

Journal of Biomechanical Science and Engineering, 2015
The line tension of the pore in a phospholipid bilayer is important for pore-mediated molecular transport techniques. To understand the cholesterol effects on the line tension of the pore edge at the molecular level, we perform molecular dynamics ...
Taiki SHIGEMATSU, Kenichiro KOSHIYAMA, Shigeo WADA   +2 more
doaj   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, Volume 38, Issue 14, 6 March 2026.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source