Results 11 to 20 of about 2,042 (179)

Vacancy Augmented Piezo‐Sonosensitizer for Cancer Therapy

Advanced Science, 2023
AbstractSonodynamic therapy (SDT) has been widely reported as a noninvasive and high‐penetration therapy for cancer; however, the design of an efficient sonosensitizer remains an urgent need. To address this issue, molybdenum disulfide nanoflowers (MoS2 NF) as piezo‐sonosensitizers and introduced sulfur vacancies on the MoS2 NF (Sv‐MoS2 NF) to improve ...
Qingyuan Wu, Jie Zhang, Xueting Pan, Zhijun Huang, Haoyuan Zhang, Juan Guo, Yun Xue, Rui Shi, Huiyu Liu   +8 more
openaire   +4 more sources

Engineered Nature-Based Sonosensitizer for Broad-Spectrum Infectious Tissue Repair via Sono-Ionic Therapy. [PDF]

Exploration (Beijing)
Repairing infectious tissues, particularly bone and wound infections, poses significant challenges to clinicians due to the lack of effective treatment modalities.
Ma L, Wang H, Liang W, Xu T, Lei J, Zhang L, Gao S, Cai X, Li Q, Wang W, Xun C, Sheng W, Yang C, Wang Y.   +13 more
europepmc   +2 more sources

Nanoparticle-Assisted Sonosensitizers and Their Biomedical Applications

International Journal of Nanomedicine, 2021
As a non-invasive strategy, sonodynamic therapy (SDT) which utilizes sonosensitizers to generate reactive oxygen species (ROS) has received significant interest over recent years due to its ability to break depth barrier. However, intrinsic limitations of traditional sonosensitizers hinder the widespread application of SDT.
Zhao,Pengxuan, Deng,Youbin, Xiang,Guangya, Liu,Yani   +3 more
openaire   +5 more sources

Piezo-Augmented Sonosensitizer with Strong Ultrasound-Propelling Ability for Efficient Treatment of Osteomyelitis

, 2022
The successful treatment of osteomyelitis remains a great challenge in the field of orthopedics. The clinical method for treating refractory bone infection requires a combination therapy of long-term systemic antibiotics administration and surgical ...
Yu Song, Liang Ma (37793), Qunle Ouyang (11972564), Jie Lei (579923), Xiangmei Liu, Jie Lei, Xiaoguang Zhang, Xiangmei Liu (307914), Gaocai Li, Yuxuan Zeng, Cao Yang, Cao Yang (370634), Xiaobo Feng, Yuxuan Zeng (10835813), Yue Luo (728594), Yu Song (316955), Lei Tan (211429), Gaocai Li (9468203), Xiaobo Feng (2183406), Xiaoguang Zhang (1397257), Qunle Ouyang, Lei Tan, Liang Ma, Yue Luo   +23 more
core   +2 more sources

Synergistic Efficacy of Ultrasound, Sonosensitizers and Chemotherapy: A Review [PDF]

Therapeutic Delivery, 2017
Chemotherapeutic agents, either in the form of systemically injected free drug or encapsulated in nanoparticles transport vehicles, must overcome three main obstacles prior to reaching and interacting with their intended target inside tumor cells.
Hirschberg, Henry, Madsen, Steen J
openaire   +4 more sources

A Comprehensive Review of Inorganic Sonosensitizers for Sonodynamic Therapy

International Journal of Molecular Sciences, 2023
Sonodynamic therapy (SDT) is an emerging non-invasive cancer treatment method in the field of nanomedicine, which has the advantages of deep penetration, good therapeutic efficacy, and minimal damage to normal tissues. Sonosensitizers play a crucial role in the process of SDT, as their structure and properties directly determine the treatment outcome ...
Peng Chen, Ping Zhang, Navid Hussain Shah, Yanyan Cui, Yaling Wang   +4 more
openaire   +2 more sources

Tumor Microenvironment Triggered the In Situ Synthesis of an Excellent Sonosensitizer in Tumor for Sonodynamic Therapy

, 2022
An ultrasound-triggered sonodynamic therapy has shown great promise for cancer therapy. However, its clinical applications are very limited because the traditional sonosensitizers tend to suffer from very poor efficiency combined with low retention in ...
Fan Gao (130617), Wei You (474340), Lei Xia (345120), Chun-Yan Hong (1588348), Ya-Qi Zhu (12815282), Yue Yu (260119), Zong-Yao Hao (5646395), Long-Hai Wang (1442521), Ye-Zi You (1442518), Guang Chen (25155), Ze Zhang (47230), Wei-Qiang Huang (3626279), Xuan Nie (7289255), Jing Chen (4762)   +13 more
core   +1 more source

Investigation of Sonosensitizers Based on Phenothiazinium Photosensitizers

Applied Sciences, 2022
The main advantage of sonodynamic therapy (SDT), the combining of ultrasound with a sonosensitizer, over photodynamic therapy (PDT) is that ultrasound penetrates deeper into tissues to activate the sonosensitizer, which offers noninvasive therapy for tumors in a site-oriented approach.
Cheng-Chung Chang, Chia-Feng Hsieh, Hsing-Ju Wu, Mohamed Ameen, Tun-Pin Hung   +4 more
openaire   +2 more sources

Molecular Sonosensitizer-Loaded Polymer Nanomicelle for Ultrasound-Based Cell Therapy via Singlet Oxygen Generation

, 2023
Ultrasound-based sonodynamic therapy has great potential for the wireless treatment of human diseases that exploit sound-responsive materials such as microbubbles, piezoelectric nanoparticles, and molecular sonosensitizers.
Nikhil R. Jana (1268586), Abu Raihan Sarkar (17364488)   +1 more
core   +1 more source

Organic Sonosensitizers-based SDT with enhanced ROS generation. [PDF]

Ultrason Sonochem
Organic sonosensitizer-based sonodynamic therapy (SDT) is an emerging, non-invasive strategy for cancer treatment, leveraging ultrasound (US) activation to trigger reactive oxygen species (ROS) production and induce tumor cell apoptosis. However, the clinical translation of SDT is limited by two key factors: the intrinsically low ROS quantum yield of ...
Shan Q, Li R, Ying B, Zhu W, Wu X, Xu S, Zhang X, Xu Z, Zhu X, Chen W, Zhang K, Chen J.   +11 more
europepmc   +3 more sources