Results 21 to 30 of about 2,042 (179)

Metallic phase enabling MoS2 nanosheets as an efficient sonosensitizer for photothermal-enhanced sonodynamic antibacterial therapy

, 2022
Two-dimensional (2D) transition metal dichalcogenide (TMD) nanosheets (e.g., MoS2) with metallic phase (1T or 1T´ phase) have been proven to exhibit superior performances in various applications as compared to their semiconducting 2H-phase counterparts ...
Chen, Huizhi, He, Xiaojun, Shen, Jianliang, Peng, Xinsheng, Wu, Zhikang, Li, Hai, Zhou, Zhan, Zhou, Yubin, Tan, Chaoliang   +8 more
core   +1 more source

Biomimetic Nanovesicle with Mitochondria-Synthesized Sonosensitizer and Mitophagy Inhibition for Cancer Sono-Immunotherapy

, 2023
Mitochondria are crucial for both sonodynamic therapy and antitumor immunity. However, how to accurately damage mitochondria and meanwhile prevent the mitophagy and immune checkpoint inhibition is still a great challenge.
Wan-Ru Zhuang (12605578), Songmao Yu (14855962), Danshu Shi (3596852), Xin Sui (211430), Hai-Yan Xie (1956682), Chao Liang (420436), Liping Zuo (3930545), Yongheng Li (2866517), Guanghao Wu (6372860), Weidong Nie (5883425), Sucheng Li (14855965)   +10 more
core   +1 more source

Ultrasound activatable antiangiogenic sonosensitizer for VEGFR associated glioblastoma tumor models

, 2021
Angiogenic signaling pathway is a major contributing factor in cancer recurrence and progression, which can cause significantly reduced treatment outcomes, especially in the oxygen‐dependent photo‐ and sonodynamic therapies. VEGF and its receptor (VEGFR)
Chuangli Zhang, Subin Son, Paramesh Jangili, Miae Won, Jiasheng Wu, Jong Seung Kim, Minhyeok Choi   +6 more
core   +1 more source

Sonosensitizer‐Functionalized Graphene Nanoribbons for Adhesion Blocking and Sonodynamic Ablation of Ovarian Cancer Spheroids

, 2021
Advanced stage ovarian cancer is challenging to treat due to widespread seeding of tumor spheroids throughout the mesothelial lining of the peritoneal cavity. In this work, a therapeutic strategy using graphene nanoribbons (GNR) functionalized with 4-arm
Victoria O. Jones, Azarin, Samira M., Dae Woo Kim, Choi, Yunkyu, Samira M. Azarin, Kim, Dae Woo, Geller, Melissa A., Jones, Victoria, Vivian E. Ferry, Melissa A. Geller, Ferry, Vivian E., Lee, Hak Rae, Hak Rae Lee, Yunkyu Choi   +13 more
core   +1 more source

Oncolytic Impediment/Promotion Balance Disruption by Sonosensitizer-Free Nanoplatforms Unfreezes Autophagy-Induced Resistance to Sonocatalytic Therapy

, 2022
Autophagy as a double-edged sword features an oncolytic impediment/promotion balance, which manipulates tumor progression. From this perspective, a sonosensitizer-free targeting oncolytic nanoplatform (SFTON) consisting of chloroquine (CQ) and porphyrin ...
Xinyu Liu (34266), Xiaohong Xu (180651), Li Song (34475), Xin Yu (124814), Chunxia Su (423328), Cheng Qian (132529), Kun Zhang (108291), Fubo Chen (13214632), Chao Fang (456315), Lu Lu (392), Zheng Lv (5781647), Yujia Fang (12611239), Taixia Wang (10901282)   +12 more
core   +1 more source

Development and characteristics of novel sonosensitive liposomes for vincristine bitartrate [PDF]

Drug Delivery, 2019
The aim of drug delivery is to increase therapeutic efficacy. Externally triggered drug delivery systems enable site-specific and time-controlled drug release. To achieve this goal, our strategy was based on ultrasound-triggered release of an anticancer agent from sonosensitive liposomes (SL).
Wen Lin, Xiaoxing Ma, Chaopei Zhou, Hong Yang, Yang Yang, Xiangyang Xie, Chunrong Yang, Cuiyan Han   +7 more
openaire   +3 more sources

Ultrasound-activated dual-targeted liposomes for visualized precise neuromodulation against myocardial ischemia-reperfusion injury. [PDF]

Mater Today Bio
Myocardial ischemia-reperfusion (I/R) injury remains a critical clinical challenge with limited effective treatments. Sympathetic hyperactivation and microglia-mediated neuroinflammation in the paraventricular nucleus exacerbate myocardial I/R injury ...
Hu H, Yao W, Wu H, Li Q, Guo W, Pang Y, Jiang H, Sun Y, Chen WH, Wang S.   +9 more
europepmc   +2 more sources

Sonosensitive MRI Nanosystems as Cancer Theranostics: A Recent Update [PDF]

Frontiers in Chemistry, 2018
In the tireless search for innovative and more efficient cancer therapies, sonosensitive Magnetic Resonance Imaging (MRI) agents play an important role. Basically, these systems consist of nano/microvesicles composed by a biocompatible membrane, responsive to ultrasound-induced thermal or mechanical effects, and an aqueous core, filled up with a MRI ...
Garello, Francesca, Terreno, Enzo
openaire   +4 more sources

Theranostic of orthotopic gliomas by core-shell structured nanoplatforms [PDF]

, 2022
Smart designed core-shell nanostructures formed by a YVO(4): Nd(3+) nanoparticle as the core, the sonosensitizer hematoporphyrinmonomethyl ether as the carrier, and MnO(2) nanosheets as the shell demonstrate bimodal imaging and highly efficient ...
Carlos, Luís D., Carlos, L.D.
core   +1 more source

Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation

, 2022
Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic malignancies, and effective treatments are still lacking due to drug tolerance and tumor recurrence.
Jing Zheng (65946), Yixuan Sun (503279), Zhu Yang (756364), Dong Yuan (6338567), Ni Zhang (503928), Tengfei Long (4418764), Song Yue (2109991)   +6 more
core   +1 more source