Results 31 to 40 of about 2,042 (179)

Ultrasound Triggers Hypericin Activation Leading to Multifaceted Anticancer Activity [PDF]

, 2022
The use of ultrasound (US) in combination with a responsive chemical agent (sonosensitizer) can selectively trigger the agent’s anticancer activity in a process called sonodynamic therapy (SDT). SDT shares some properties with photodynamic therapy (PDT),
Panzanelli, Patrizia, Roberto Canaparo, Patrizia Panzanelli, Federica Foglietta, Simone Cossari, Franco Dosio, Canaparo, Roberto, Cossari, Simone, Dosio, Franco, Foglietta, Federica, Loredana Serpe, Serpe, Loredana   +11 more
core   +1 more source

Rose Bengal Promoted Catalytic Amyloid-β Oxygenation via Sono-Activation [PDF]

, 2023
Catalytic photo-oxygenation of amyloid-β is a leading therapeutic strategy for the treatment of Alzheimer disease. However, the limited tissue-permeability of light hampers its clinical application.
Miku, Oi, Youhei, Sohma, Motomu, Kanai, Keiichi, Kawabata, Yukiko, Hori, Wataru, Atsumi, Mina, Yamane, Taisuke, Tomita, Harunobu, Mitsunuma   +8 more
core   +1 more source

Exploiting lipid and polymer nanocarriers to improve the anticancer sonodynamic activity of chlorophyll [PDF]

, 2020
Sonodynamic therapy is an emerging approach that uses low-intensity ultrasound to activate a sonosensitizer agent triggering its cytotoxicity for selective cancer cell killing.
Foglietta, F., Serpe, L., Federica Bosca, Alberto Gimenez, Barbara Stella, Loredana Serpe, Bosca, F., Arpicco, S., Barge, A., Roberto Canaparo, Alessandro Barge, Silvia Arpicco, Canaparo, R., Giovanni Durando, Federica Foglietta, Ilaria Andreana, Peira, E., Elena Peira, Stella, B., Andreana, I.   +19 more
core   +1 more source

Apoptosis of THP-1 derived macrophages induced by sonodynamic therapy using a new sonosensitizer hydroxyl acetylated curcumin.

, 2014
Curcumin is extracted from the rhizomes of the traditional Chinese herb Curcuma longa. Our previous study indicated curcumin was able to function as a sonosensitizer.
Yang, Liming, Wenhui Guo, Sun, Xinyong, Zhu, Xing, Longbin Zheng, Zheng, Longbin, Xinyong Sun, Liming Yang, Guo, Wenhui, Feng Zhang, Zhong, Zhaoyu, Zhaoyu Zhong, Cao, Wenwu, Xing Zhu, Ye Tian, Wenwu Cao, Fengxiang Lv, Tian, Ye, Lv, Fengxiang, Zhang, Feng   +19 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes

Biomedicines, 2022
Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model fitting was performed for a large dataset of liposomal release profiles with seven targeting moieties (albumin, cRGD, estrone ...
Zeyad AlMajed, Najla M. Salkho, Hana Sulieman, Ghaleb A. Husseini   +3 more
openaire   +3 more sources

Facile Synthesis of a Cubic Porphyrin-Based Covalent Organic Framework for Combined Breast Cancer Therapy

, 2021
A cubic porphyrin-based covalent organic framework (COF) named CTP with excellent hydrophilicity was prepared with a facile method for the first time. Different from the conventional methods for the synthesis of porphyrin-based COFs, this facile strategy
Maolin Pang (1935004), Qi Meng (262900), Zhendong Liu (1235259), Changxiao Chen (11731663), Sainan Liu (6491270)   +4 more
core   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

SONODYNAMIC THERAPY USING DACARBAZINE-LOADED AUSIO(2) NANOPARTICLES FOR MELANOMA TREATMENT: AN IN-VITRO STUDY ON THE B16F10 MURINE MELANOMA CELL LINE

, 2022
The use of nanoparticles as a sonosensitizer in cancer sonodynamic therapy has been gaining attention because of their great advantages in drug delivery applications.
Esmailzadeh, A., Shanei, A., Hejazi, S. H., Hemati, S., Attaran, N.   +4 more
core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source