Results 81 to 90 of about 417,784 (319)

Order-sorted completion: the many-sorted way [PDF]

open access: yesTheoretical Computer Science, 1989
The author improves previous results about the relation between order- sorted and many-sorted rewriting. In particular it has been shown that one step of order-sorted rewriting with a set of rules \(R\) is one step of many-sorted rewriting with the lowest parse of the sort specialization \(R/s/\) of \(R\) modulo the axioms \(LP\) of the lowest parse ...
openaire   +5 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Sorting It Out: Review of The Big Sort [PDF]

open access: yesCalifornia Journal of Politics and Policy, 2009
Cain: Sorting It Out: Review of The Big Sort THE CALIFORNIA Journal of Politics & Policy Book Review The Big Sort: Why the Clustering of Like-Minded Americans Is Tearing Us Apart; Bill Bishop and Robert G. Cushing, Houghton Mifflin, 2008 Sorting It Out Bruce E.
openaire   +4 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Pulse interference method against PRI sorting

open access: yesThe Journal of Engineering, 2019
Based on the purpose of proactive anti-reconnaissance, the essential characteristics of several typical pulse repetition interval (PRI) sorting algorithms were analysed and the feasibility of counter-deinterleaving was discussed.
Hao Nan   +3 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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