Results 61 to 70 of about 141,828 (307)

Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons [PDF]

, 2011
Background: Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathogens.
Barbé García, Jordi, Cambray, Guillaume, Campoy Sánchez, Susana, Da Re, Sandra, Erill, Ivan, González Zorn, Bruno, Guerin, Émilie, Mazel, Didier, Ploy, Marie-Cécile, Sánchez Alberola, Neus   +9 more
core   +10 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Effects of Climate Extremes on Spring Phenology of Temperate Vegetation in China

Remote Sensing, 2023
The response of vegetation spring phenology to climate warming has received extensive attention. However, there are few studies on the response of vegetation spring phenology to extreme climate events.
Yunhua Mo, Xuan Zhang, Zunchi Liu, Jing Zhang, Fanghua Hao, Yongshuo Fu   +5 more
doaj   +1 more source

Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response [PDF]

, 2008
The DNA damage induced SOS response in Escherichia coli is initiated by cleavage of the LexA repressor through activation of RecA. Here we demonstrate that overexpression of the SOS-inducible tisAB gene inhibits several SOS functions in vivo. Wild-type E.
Bjørås, Magnar, Kristiansen, Knut Ivan, Weel-Sneve, Ragnhild   +2 more
core   +4 more sources

Stretching‐Orientation Reinforced Double Network Solvent‐Free Eutectic Gels for Ultrarobust, Flexible Human‐Machine Interaction Devices

Advanced Functional Materials, EarlyView.
This work develops an ultrarobust, flexible, and solvent‐free eutectic gel featuring stretch‐induced orientation. Overcoming hydrogel limitations, the gel achieves record toughness (133.86 MJ m−3) while integrating strain/temperature/capacitive sensing.
Tingzhong Li, Tongyuan Liu, Qinglu Yu, Yasen Li, Rui Liang, Guoxing Sun   +5 more
wiley   +1 more source

Cottonseed‐Derived Reusable Bio‐Carbon Gel Ink for DIW Printing Soft Electronic Textiles

Advanced Materials, EarlyView.
A reusable carbon‐gel ink, incorporating cottonseed peptone as a natural mediator, enables cross‐linked ionic polymer networks for advanced conductivity, stability, and biocompatibility. Compatible with direct‐ink‐writing, it facilitates flexible electronics on polymeric and textile substrates for multifunctional applications, including motion sensing,
King Yan Chung, Di Tan, Ziyu He, Xiao Li, Jian Lu, Qingjun Yang, Xinlong Liu, Bingang Xu   +7 more
wiley   +1 more source

Analysis of triacylglycerol and phospholipid sn‐positional isomers by liquid chromatographic and mass spectrometric methodologies

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Analysis of triacylglycerol (TG) and phospholipid sn‐positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods.
Mikael Fabritius, Baoru Yang
wiley   +1 more source

3D Printing of Auxetic Self‐powered Mechanoluminescent Photonic Skins for Underwater Communication and Safety Monitoring

Advanced Materials, EarlyView.
A 3D‐printed self‐powered auxetic mechanoluminescent photonic skin for underwater communication and safety monitoring is introduced. Its auxetic structures, with a negative Poisson's ratio, ensure exceptional conformability to curved surfaces, enhancing adaptability to dynamic underwater environments.
Xiaolu Sun, Shaohua Ling, Zhihang Qin, Jinrun Zhou, Quangang Shi, Zhuangjian Liu, Yu Jun Tan   +6 more
wiley   +1 more source

Dual Roles of Deep Eutectic Solvent in Polysulfide Redox and Catalysis for Intermediate‐Temperature Potassium‐Sulfur Batteries

Advanced Materials, EarlyView.
A dual‐functional NiS‐DES interfacial strategy enables highly reversible K2S2/K2S conversion in intermediate‐temperature K‐S batteries by balancing adsorption and activation of intermediates at the catalytic interface, achieving high capacity, long cycle life, and low‐cost energy storage. Abstract Potassium–sulfur (K‐S) batteries hold great promise for
Liying Tian, Qian Wu, Kai Tang, Zhiqiang Tang, Zhenghao Yang, Zihan Shen, Longcheng Zhang, Wen Xie, Yuan Yang, Zhichuan J. Xu   +9 more
wiley   +1 more source