Results 51 to 60 of about 29,159 (246)
Advanced Science, EarlyView.High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld +5 more
wiley +1 more source
Upstream of the SOS response: figure out the trigger [PDF]
Trends in Microbiology, 2006 The bacterial SOS regulon encodes a response to DNA damage that not only functions to relieve the incurred damage but also enhances adaptation through mutagenesis and the lateral spread of virulence factors. Recent papers have demonstrated that certain stimuli can indirectly generate the SOS-inducing signal by activation of endogenous DNA damage ...
Aertsen, Abram, Michiels, Christiaan
openaire +3 more sources
Advanced Science, EarlyView.Metal‐anode batteries using Li, Na, Mg, and Ca offer exceptionally high energy density, but dendrites, unstable interphases, cracking, and pore formation hinder durability and safety. This review shows how careful electrolyte and interphase design can stabilize these reactive metals.
Jian Pan +3 more
wiley +1 more source
Integration of Reconfigurable p‐Bit and 1R Crossbar Array for Memristive Probabilistic Computing
Advanced Science, EarlyView.A memristive probabilistic computing system is demonstrated by integrating stochastic p‐bits based on volatile memristors with a 1R crossbar array encoding interaction weights. The system performs weighted‐sum operations across the array and updates p‐bits iteratively.
Keunho Soh +7 more
wiley +1 more source
Bacteria under SOS evolve anticancer phenotypes
Infectious Agents and Cancer, 2010 Background The anticancer drugs, such as DNA replication inhibitors, stimulate bacterial adhesion and induce the bacterial SOS response. As a variety of bacterial mutants can be generated during SOS, novel phenotypes are likely to be selected under the ...
Weitao Tao, Dallo Shatha F
doaj +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Inducible SOS Response System of DNA Repair and Mutagenesis in Escherichia coli
International Journal of Biological Sciences, 2008 Chromosomal DNA is exposed to continuous damage and repair. Cells contain a number of proteins and specific DNA repair systems that help maintain its correct structure.
Celina Janion
doaj
Effects of Climate Extremes on Spring Phenology of Temperate Vegetation in China
Remote Sensing, 2023 The response of vegetation spring phenology to climate warming has received extensive attention. However, there are few studies on the response of vegetation spring phenology to extreme climate events.
Yunhua Mo +5 more
doaj +1 more source
Response to ‘Not-so-simple setae’ [PDF]
Journal of Experimental Biology, 2011 In his Correspondence article ([p. 871][1]), DeForest Mellon, Jr argues that the type of seta in our report ([Monteclaro et al., 2010][2]) was erroneously identified. In response, we would like to make the following remarks.
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Robust Stitching Interface and Deep Learning Empowered Hydrogel Human‐Machine Interface
Advanced Science, EarlyView.A molecular design strategy is presented that exploits synergistic carboxylate anion–quaternary ammonium interactions to simultaneously strengthen the hydrogel–PET interface and the bulk hydrogel network. Integrated with deep learning signal processing, the stable hydrogel–PET interface enables consistent signal acquisition and reliable human‐machine ...
Hao Dong +11 more
wiley +1 more source