Results 161 to 170 of about 625,297 (304)

Programmable 3D Microfluidics Reveals Motility‐Driven Antibiotic Resistance Evolution in Gradients

Small, EarlyView.
Using a programmable microfluidic platform, this study shows that bacterial motility is crucial for resistance development in heterogeneous antibiotic landscapes. Motile Escherichia coli randomly migrates along antibiotic gradients, and sufficient movement is required for resistance to emerge.
Xiaobo Li, Jianan Yin, Yanqing Song, Andrew Glidle, William Sloan, He Huang, Maggie Cusack, Cindy J. Smith, Huabing Yin   +8 more
wiley   +1 more source

STRATEGI DESENTRALISASI KESEJAHTERAAN SOSIAL DALAM RANGKA OTONOMI DAERAH

, 2016
Kebijakan publik mengenai desentralisasi sesuai dengan aturan dan semangat Undang - Undang Nomor 22 Tahun 1999, membawa implikasi luas terhadap implementasi kebijakan kesejahteraan sosial di Indonesia.
Nuryana, Mu'man
core   +1 more source

A Preliminary Exploratory Measurement Model for Systems Thinking in Defence and Aerospace Engineering: A Bifurcated Framework Developed via Multiple Correspondence Analysis

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Modern engineering faces a ‘complexity crisis’ characterized by interlinked, multidisciplinary ‘wicked problems’, particularly within the defence and aerospace sectors. Although systems thinking is recognized as a critical competency for navigating this environment, empirical quantitative frameworks for its measurement remain limited.
Shimon Fridkin, Sigal Kordova
wiley   +1 more source

Using Visual Systems Mapping to Improve Transparency and Comparability of Life Cycle Assessment Baseline Scenarios

Systems Engineering, EarlyView.
ABSTRACT Visual systems mapping is a systems engineering approach used to represent complex processes and interactions. This study evaluates its application for documenting assumptions in life cycle assessment (LCA) baseline scenarios. In LCA, the baseline or reference case represents the business as usual system against which changes in impacts (e.g.,
Maggie R. Davis, Steven Conrad
wiley   +1 more source

Accelerating Mission Engineering: Evidence of a Stratified Landscape and a Path Toward Unified Practice

Systems Engineering, EarlyView.
ABSTRACT Mission Engineering is maturing as a Systems Engineering discipline, yet adoption of its common frameworks remains stratified. This study examines whether selective adoption is observable across ME scholarship and develops a framework to address identified barriers.
James Moreland, Nathaniel Ambler, Casey LaMar, Maegen Nix, Craig Sawyer   +4 more
wiley   +1 more source

What Is the Return on Investment of Digital Engineering for Complex Systems Development Schedules? Findings From a Mixed‐Methods Case Study on the Post‐Production Design Change Processes of Navy Assets

Systems Engineering, EarlyView.
ABSTRACT Complex engineered systems routinely face schedule and cost overruns, along with poor post‐deployment performance. Both INCOSE and the U.S. Department of Defense (DoD) have championed Digital Engineering (DE) as a potential remedy, yet most of DE's purported benefits remain anecdotal, and its return on investment (ROI) remains poorly ...
Jannatul Shefa, Taylan G. Topcu
wiley   +1 more source

Photocatalytic and Biotechnological Strategies for Remediation of Persistent Organic Pollutants: Mechanisms, Toxicity, and Antimicrobial Perspectives

Environmental Toxicology, EarlyView.
ABSTRACT Persistent organic pollutants (POPs) pose significant ecological and human health risks due to their persistence, bioaccumulation, toxicity, and global distribution. Conventional remediation methods are often inadequate for achieving complete mineralization, demonstrating the need for advanced and substantial approaches.
Viola O. Okechukwu, Patrick B. Njobeh, Jonathan O. Okonkwo   +2 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

No gain from pain: Lack of nociceptor activation suggests no adaptation for defence in the evolution of European viper venoms

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges, Samuel D. Robinson, Vanessa Schendel, Edvárd Mizsei, Ana Ćuriċ, Maria Dimaki, Vincenzo Ferri, Silviu Petrovan, Andrea V. Pozzi, Tihomir Radonjiċ, Tibor Sos, Jeffrey W. Streicher, Alexandru Strugariu, Emina Šunje, Ștefan Zamfirescu, Oleksandr Zinenko, Irina Vetter, Wolfgang Wüster   +17 more
wiley   +1 more source

PEMIKIRAN HEGEMONI ANTONIO GRAMSCI (1891- 1937) DI ITALIA

Jurnal Yaqzhan: Analisis Filsafat, Agama dan Kemanusiaan, 2017
Gramsci mengenalkan istilah hegemoni sebagai kritik atas pemahaman marxisme tradisional dalam memahami kapitalisme yang cenderung determinisme ekonomi. Gramsci melihat pandangan marxis tradisional tersebut telah mendogma namun tanpa pembuktian.
Zezen Zaenudin Ali
doaj