Results 101 to 110 of about 23,758 (203)
Jun Li,1,* YanXia Ren,1,* SiYuan Li,2 JiaJia Li3 1Endocrinology and Metabolism Department, First Affiliated Hosptital, School of Medicine, Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region, People’s Republic of China; 2Shihezi ...
Li J, Ren Y, Li S, Li J
doaj
Identification of a DNA aptamer that inhibits sclerostin's antagonistic effect on Wnt signalling [PDF]
Sclerostin is an extracellular negative regulator of bone formation that is a recognized therapeutic target for osteoporosis therapy. In the present study, we performed DNA aptamer selection against sclerostin, then characterized aptamer-sclerostin ...
Chan, C, Leung, CM, Shum, KT, Tanner, JA
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Applying Of Activities Management Based On Self-learning [PDF]
The article is devoted to a brief presentation and application in practice of an effective management way of human activities and human-technical communities one. This way was called Method of statistical regularity (Method of self-organizing processes).
Druz’, V. (Valerii) +2 more
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Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies [PDF]
Different model systems using osteoblastic cell lines have been developed to help understand the process of bone formation. Here, we report the establishment of two human osteoblastic cell lines obtained from primary cultures upon transduction of ...
A Eddleston +46 more
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Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation [PDF]
Osteocytes are terminally differentiated osteoblasts which reside in a mineralized extracellular matrix (ECM). The factors that regulate this differentiation process are unknown.
Farquharson, C. +3 more
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Evaluation of Biomarkers in Patients with Different Periodontal Statuses
Background: The aim of this study was to compare the levels of salivary nuclear factor kappa-β receptor activator ligand (RANKL), osteoprotegerin (OPG), tumor necrosis factor alpha (TNF)-α, and sclerostin (SOST) in individuals with different periodontal ...
Fatma Uçan Yarkaç +2 more
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A novel nonosteocytic regulatory mechanism of bone modeling.
Osteocytes, cells forming an elaborate network within the bones of most vertebrate taxa, are thought to be the master regulators of bone modeling, a process of coordinated, local bone-tissue deposition and removal that keeps bone strains at safe levels ...
Lior Ofer +9 more
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Stimulation of Piezo1 by mechanical signals promotes bone anabolism [PDF]
Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood.
Almeida, Maria +6 more
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PaperRobot: Incremental Draft Generation of Scientific Ideas
We present a PaperRobot who performs as an automatic research assistant by (1) conducting deep understanding of a large collection of human-written papers in a target domain and constructing comprehensive background knowledge graphs (KGs); (2) creating ...
Bansal, Mohit +6 more
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Profiles of Wnt pathway gene expression during tooth morphogenesis
Mouse and human genetic studies indicate key roles of the Wnt10a ligand in odontogenesis. Previous studies have identified effectors and regulators of the Wnt signaling pathway actively expressed during key stages of tooth morphogenesis.
Resmi Raju +11 more
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