Results 101 to 110 of about 23,758 (203)

Relationship Between Sclerostin (SOST) Expression and Genetic Loci rs851056, rs1230399 Polymorphisms and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes in Xinjiang

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Jun Li,1,* YanXia Ren,1,* SiYuan Li,2 JiaJia Li3 1Endocrinology and Metabolism Department, First Affiliated Hosptital, School of Medicine, Shihezi University, Shihezi, Xinjiang Uygur Autonomous Region, People’s Republic of China; 2Shihezi ...
Li J, Ren Y, Li S, Li J
doaj  

Identification of a DNA aptamer that inhibits sclerostin's antagonistic effect on Wnt signalling [PDF]

open access: yes, 2011
Sclerostin is an extracellular negative regulator of bone formation that is a recognized therapeutic target for osteoporosis therapy. In the present study, we performed DNA aptamer selection against sclerostin, then characterized aptamer-sclerostin ...
Chan, C, Leung, CM, Shum, KT, Tanner, JA
core   +1 more source

Applying Of Activities Management Based On Self-learning [PDF]

open access: yes, 2018
The article is devoted to a brief presentation and application in practice of an effective management way of human activities and human-technical communities one. This way was called Method of statistical regularity (Method of self-organizing processes).
Druz’, V. (Valerii)   +2 more
core  

Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies [PDF]

open access: yes, 2017
Different model systems using osteoblastic cell lines have been developed to help understand the process of bone formation. Here, we report the establishment of two human osteoblastic cell lines obtained from primary cultures upon transduction of ...
A Eddleston   +46 more
core   +2 more sources

Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation [PDF]

open access: yes, 2012
Osteocytes are terminally differentiated osteoblasts which reside in a mineralized extracellular matrix (ECM). The factors that regulate this differentiation process are unknown.
Farquharson, C.   +3 more
core   +3 more sources

Evaluation of Biomarkers in Patients with Different Periodontal Statuses

open access: yesEssentials of Dentistry
Background: The aim of this study was to compare the levels of salivary nuclear factor kappa-β receptor activator ligand (RANKL), osteoprotegerin (OPG), tumor necrosis factor alpha (TNF)-α, and sclerostin (SOST) in individuals with different periodontal ...
Fatma Uçan Yarkaç   +2 more
doaj   +1 more source

A novel nonosteocytic regulatory mechanism of bone modeling.

open access: yesPLoS Biology, 2019
Osteocytes, cells forming an elaborate network within the bones of most vertebrate taxa, are thought to be the master regulators of bone modeling, a process of coordinated, local bone-tissue deposition and removal that keeps bone strains at safe levels ...
Lior Ofer   +9 more
doaj   +1 more source

Stimulation of Piezo1 by mechanical signals promotes bone anabolism [PDF]

open access: yes, 2019
Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood.
Almeida, Maria   +6 more
core   +1 more source

PaperRobot: Incremental Draft Generation of Scientific Ideas

open access: yes, 2019
We present a PaperRobot who performs as an automatic research assistant by (1) conducting deep understanding of a large collection of human-written papers in a target domain and constructing comprehensive background knowledge graphs (KGs); (2) creating ...
Bansal, Mohit   +6 more
core   +1 more source

Profiles of Wnt pathway gene expression during tooth morphogenesis

open access: yesFrontiers in Physiology
Mouse and human genetic studies indicate key roles of the Wnt10a ligand in odontogenesis. Previous studies have identified effectors and regulators of the Wnt signaling pathway actively expressed during key stages of tooth morphogenesis.
Resmi Raju   +11 more
doaj   +1 more source

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