Results 141 to 150 of about 11,099 (162)

Analysis of serum biomarker profiles in DDH Hip osteoarthritis versus primary hip osteoarthritis: a prospective observational study in a recent arthroplasty cohort. [PDF]

J Orthop Surg Res
Harsanyi S, Schmiedlova K, Milosovicova L, Bernatova S, Harsanyiova K, Danisovic L, Steno B.   +6 more
europepmc   +1 more source

Generation and characterization of a novel inducible Sost_P2A_CreERT2 mouse model with high specificity for osteocytes. [PDF]

JBMR Plus
Prideaux M, Kitase Y, Pelletier S, Robling AG, Bonewald LF.   +4 more
europepmc   +1 more source

Meta-Analysis of Ocy-454 Showed Interrupted Osteocyte Maturation in Spaceflight Affects SOST Expression and Hypoxic Response. [PDF]

J Clin Med
Honjo M, Hasegawa T, Muratani M, Bochimoto H.   +3 more
europepmc   +1 more source

Establishment of a human osteocyte model to reveal mechanisms of chronic Staphylococcus epidermidis bone and joint infections. [PDF]

Bone Joint Res
Siverino C, Sun Q, Solomon LB, Moriarty TF, Atkins GJ.   +4 more
europepmc   +1 more source

Life course adiposity and risk of incident osteoporosis: a prospective cohort study from the UK Biobank. [PDF]

Front Endocrinol (Lausanne)
Liu H, Zhu J, Zhang Q, Chen J, Huang R.
europepmc   +1 more source

Reversing LRP 5-Dependent Osteoporosis and SOST Deficiency–Induced Sclerosing Bone Disorders by Altering WNT Signaling Activity [PDF]

Journal of Bone and Mineral Research, 2014
The bone formation inhibitor sclerostin encoded by SOST binds in vitro to low-density lipoprotein receptor-related protein (LRP) 5/6 Wnt co-receptors, thereby inhibiting Wnt/β-catenin signaling, a central pathway of skeletal homeostasis.
Jonathan Gooi, Hansjoerg Keller
exaly   +2 more sources

SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury [PDF]

Journal of Bone and Mineral Research, 2018
Patients with anterior cruciate ligament (ACL) rupture are two times as likely to develop posttraumatic osteoarthritis (PTOA). Annually, there are ∼900,000 knee injuries in the United States, which account for ∼12% of all osteoarthritis (OA) cases.
Gabriela Loots, Blaine Christiansen, Deepa Murugesh   +2 more
exaly   +2 more sources

SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development

Developmental Dynamics, 2007
Spatial-temporal regulation of bone morphogenetic protein (BMP) and Wnt activity is essential for normal cardiovascular development, and altered activity of these growth factors causes maldevelopment of the cardiac outflow tract and great arteries.
Rui Monteiro, Christine Mummery, Peter Ten Dijke   +2 more
exaly   +2 more sources

Novel SOST gene mutation in a sclerosteosis patient and her parents

Bone, 2013
: Introduction Sclerosteosis (OMIM 269500) is a rare autosomal recessive condition characterized by increased bone density associated with syndactyly. It is linked to a genetic defect in the SOST gene coding for sclerostin.
Vandana Dhiman, Sanjay Kumar Bhadada, Wim van Hul   +2 more
exaly   +1 more source

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An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling

Calcified Tissue International, 2023
Gretl Hendrickx, Geert Mortier, Timur Yorgan   +2 more
exaly