Results 151 to 160 of about 59,986 (306)

Seven Sisters - A Kentucky Portrait

, 2000
A documentary film on seven sisters from West Liberty, Kentucky.
Donahew, John Patrick, Sour Mash Films
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Origin-Associated Variation in Volatile Profiles of Commercial Sour Jujube Pulp. [PDF]

Foods
Chen N, Wu X, Dai O, Zhang B, Xuan S, Xie F, Chen Y, Wang F, Zhang L.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Exploring phenotypic diversity and constructing a floral core collection of <i>Ziziphus jujuba</i> var. <i>spinosa</i>. [PDF]

PeerJ
Wang Y, Zhang Y, Sun Y, Wang K, Zhao X, Chen J, Dong S.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Impact of KCl-divalent salt synergistic substitution on protease activity and volatile flavor profile in sodium-reduced sour meat. [PDF]

Food Chem X
Chen Y, Liu N, Guan Y, Bi S, Shang L, Yang C, Li C, Liu Y, Xu B, Zhu Q, Zhou Y.   +10 more
europepmc   +1 more source

Sour Lake

, 1955
Photograph shows Sour Lake, a mineral lake that was a destination for 19th century health-seekers.Title from caption, page 189, in photographer's book, Sam Houston's Texas, published in 1964, for which this photograph was ...
Flanagan, Sue; Hardin County, Tex.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Fauna Ibérica, vol. 27. Lophophorata: Phoronida, Brachiopoda

Revista Mexicana de Biodiversidad, 2006
FRANCISCO SOUR TOVAR
doaj   +1 more source