Results 51 to 60 of about 166,223,834 (257)

Review article: the governance of activation [PDF]

, 2008
This article presents a review of relevant literature on the issue of the governance of activation. The article starts with some general comments on the state of the art of research on the governance of activation.
BORGHI, VANDO, LSG Management of Meaning (MOM), Borghi, V., Rik van Berkel, Management of Meaning, R. van Berkel, van Berkel, H.H.A., Vando Borghi   +7 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Means for Evaluation of Light Source Characteristics

Elektronika ir Elektrotechnika, 2013
Light emitting diodes have many positive features comparing with incandescent and fluorescent lamps like its small size; high luminous efficiency, long lifetime and reliability. That features increases the popularity of LEDs using in lighting. However there are many cheap, non-certified light emitting diodes bulbs in the market, where the parameters of
Markevicius, V., Cepenas, M., Navikas, D., Valinevicius, A., Andriukaitis, D., Surgailis, T., Kauno technologijos universitetas   +6 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Clients’ Faith Experiences as an Opportunity or a Challenge for Psychotherapy: A Qualitative Analysis of Clinical Records

Religions, 2020
Faith experiences constitute important sources of meaning but also a risk of religious struggles. However, studies exploring the faith experiences of clients in relation to psychological functioning in psychotherapy are needed, especially in secularized ...
Aida Hougaard Andersen, Dorte Toudal Viftrup, Heidi Frølund Pedersen, Kirsten K. Roessler   +3 more
doaj   +1 more source

THE SOURCE OF THE LYMPHOCYTOSIS INDUCED BY MEANS OF HEAT [PDF]

Journal of Experimental Medicine, 1919
A striking number of mitotic figures have been observed in the germinal center of the spleen and lymph glands during the regeneration of the cellular elements of these organs after the destructive effect of heat. This enhanced cell proliferation is interpreted as more than compensating for the degenerated cells, because of the subsequent enlargement of
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source