Results 101 to 110 of about 71,666 (215)

AVPV neurons containing estrogen receptor-beta in adult male rats are influenced by soy isoflavones

open access: yesBMC Neuroscience, 2007
Background Isoflavones, the most abundant phytoestrogens in soy foods, are structurally similar to 17beta-estradiol. It is known that 17beta-estradiol induces apoptosis in anteroventral periventricular nucleus (AVPV) in rat brain. Also, there is evidence
Bu Lihong, Lephart Edwin D
doaj   +1 more source

High‐throughput image‐based phenotyping of soybean hilum color

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Hilum color in soybean (Glycine max [L.] Merr.) is an important morphological trait influencing market classification and seed quality traits, yet its phenotyping is largely subjective, relying on visual inspection and assignment to one of eight color classes. This study developed an image‐based high‐throughput pipeline to measure and classify
Katherine Fortune   +2 more
wiley   +1 more source

The Effects of Soy Protein and Cocoa With or Without Isoflavones on Glycemic Control in Type 2 Diabetes. A Double-Blind, Randomized, Placebo-Controlled Study

open access: yesFrontiers in Endocrinology, 2019
Objective: Soy and cocoa have been suggested to be beneficial for diabetes. The aim of this study was to identify the effects of soy protein, isoflavones, and cocoa on glycemic control parameters.Research design and methods: The study was a parallel ...
Judit Konya   +3 more
doaj   +1 more source

Application of Omics Technologies for Cowpea Improvement

open access: yesPlant-Environment Interactions, Volume 7, Issue 5, October 2026.
ABSTRACT Cowpea (Vigna unguiculata) is a vital crop for food security, nutrition, and climate resilience in sub‐Saharan African and other semi‐arid regions. However, its improvement is constrained by the complexity of polygenic traits such as drought tolerance, pest resistance, and seed quality.
Junior S. Kamara   +3 more
wiley   +1 more source

Menopausal symptoms: from soy isoflavones to combined soy-exercise interventions [PDF]

open access: yes, 2019
Diet and physical activity affect menopausal symptoms. We aimed to review recent evidence based on clinical trials and meta-analysis on the effect of soy isoflavones on menopausal symptoms and the potential synergistic effect of soy consumption and ...
Paola Aiello   +4 more
core  

Unveiling the Diagnostic Value and Potential Therapeutic Targets of Phenylalanine Metabolism in Pancreatic Cancer via Integrated Multi‐Omics and Machine Learning

open access: yesThe FASEB Journal, Volume 40, Issue 18, 30 September 2026.
MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu   +3 more
wiley   +1 more source

Rodent Models Assessing Mammary Tumor Prevention by Soy or Soy Isoflavones

open access: yes, 2019
While epidemiological studies performed in Asian countries generally show that high levels of dietary soy are associated with reduced breast cancer risk, studies in Western countries have typically failed to show this correlation.
Roger A. Moorehead
core   +1 more source

Structure‐Guided Optimization of PDE9A Inhibitors Tackling Neuroinflammation: A Combined Computational and In Vitro Study

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
Computational studies allowed the identification of a PDE9A inhibitor. A novel HPLC‐based assay was developed and optimized to measure enzyme function to assess PDE9A inhibition. Furthermore, in vitro tests supported the activity of the compound against neuroinflammation. Oxidative stress and inflammation are key players in central nervous system (CNS)
Giovanni Ribaudo   +10 more
wiley   +1 more source

Inactivation of thyroid peroxidase by soy isoflavones in vitro and in vivo.

open access: yes, 2012
[[abstract]]Soy-containing foods and dietary supplements are widely consumed for putative health benefits (e.g. cancer chemoprevention, beneficial effects on serum lipids associated with cardiovascular health, reduction of osteoporosis, relief of ...
張竣維;Hebron, C.Chang
core  

Traditional and Domestic Cooking Dramatically Reduce Estrogenic Isoflavones in Soy Foods

open access: yesFoods
Soybean is a pulse which has considerable nutritional value due to its high protein, fibers and polyunsaturated fatty acid (PUFA) contents. It also contains phytoestrogenic compounds that definitely hinder its recommendation for general consumption ...
Souad Bensaada   +4 more
doaj   +1 more source

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