Results 81 to 90 of about 3,830,532 (256)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

High protein diets containing whey protein concentrate and soy protein isolate improve insulin resistance and reduce weight and fat gain in obese minipigs

, 2005
High protein diets containing whey protein concentrate and soy protein isolate improve insulin resistance and reduce weight and fat gain in obese ...
B Tatham (13299462), I McCauley (13299465), F Dunshea (13293273), D Kerton (13299471), E Ostrowska (13293267), J Ferrari (13299456), M Cox (9875711), P Eason (13299468), Morley Muralitharan (13085757)   +8 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Fermentation Improves Protein Content and Physicochemical Characteristics of Tempe Protein Concentrate Compared to Soy Protein [PDF]

The growing demand for sustainable plant-based proteins has increased interest in fermented soy products due to their improved nutritional and functional properties. This study investigated the effect of fermentation on the physicochemical and functional
Saraswati, Saraswati, Prayudani, Ayu Putri Gitanjali, Yalmaida, Nabila Az Zahra, Astawan, Made, Damayanti, Aprilia Firdha, Wresdiyati, Tutik   +5 more
core   +1 more source

Alcohol- and water-extracted soy protein concentrates for early-weaned pigs [PDF]

, 1994
A total of 72 weanling pigs (average initial wt of 7 lb and 10 d of age) was used in a 38-d growth assay to determine the nutritional value of alcohol- and water-extracted soy protein concentrates.
Hines, Robert H., Kim, I.H., I H Kim, Joe D Hancock, Hancock, Joe D, Kim, I H, Cabrera, M.R., M R Cabrera, Hancock, Joe D., Robert H Hines, Hines, Robert H, L L Burnham, Burnham, L.L., Burnham, L L, Cabrera, M R   +14 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Replacing Soybean Meal with Soy Protein Concentrate in Diets Containing 12% Crude Protein Does Not Maintain Performance in Finishing Pigs from 240 to 280 lb [PDF]

, 2018
A total of 252 pigs (DNA 600 × 241, initially 238.8 lb) were used in a 21-d trial to determine the effects of replacing soybean meal (SBM) with soy protein concentrate (SPC) in diets containing 12% crude protein (CP) on growth performance of finishing ...
Woodworth, J. C., J. C. Woodworth, J. A. Soto, S. S. Dritz, J. M. DeRouchey, Goodband, R. D., Soto, J. A., Dritz, S. S., M. D. Tokach, DeRouchey, J. M., R. D. Goodband, Tokach, M. D.   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Vegetable proteins in microencapsulation: a review of recent interventions and their effectiveness [PDF]

, 2013
Proteins from vegetable seeds are interesting for research at present because they are an abundant alternative to animal-based sources of proteins and petroleum-derived polymers.
Alric, Isabelle, Silvestre, Françoise, Durrieu, Vanessa, Nesterenko, Alla   +3 more
core   +1 more source