Results 51 to 60 of about 344,689 (311)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Soy Notes Soy Notes, for the Kansas Soybean Farmer

, 2019
The Kansas Soybean Commission and the Kansas Soybean Association – two distinct organizations that work together for Kansas soybean farmers. They aim to expand existing markets; develop new uses; facilitate agronomic research; and communicate goals and ...
Kansas Soybean Commission
core   +1 more source

Genome-wide identification, characterization, and expression analysis of the plant defensin (PDF) gene family in soybean

BMC Plant Biology
Plant defensins (PDFs) are small, cysteine-rich antimicrobial peptides that play central roles in plant innate immunity. Despite their importance, a systematic characterization of the PDF gene family in soybean (Glycine max) has been lacking.
Rongqiang Yuan, Chunlei Zhang, Tianjiao Gao, Xiulin Liu, Xueyang Wang, Fengyi Zhang, KeZhen Zhao, XiaoYu Xia, Sobhi F. Lamlom, Honglei Ren   +9 more
doaj   +1 more source

Integration of physiological and transcriptomic approaches in investigating salt-alkali stress resilience in soybean

Plant Stress
Salt-alkali stress is a key factor affecting plant development and production, altering essential physiological and metabolic processes within plants.
Honglei Ren, Bixian Zhang, Fengyi Zhang, Xiulin Liu, Xueyang Wang, Chunlei Zhang, Kezhen Zhao, Rongqiang Yuan, Sobhi F. Lamlom, Ahmed M. Abdelghany, Jiajun Wang   +10 more
doaj   +1 more source

Cytoplasm Types Affect DNA Methylation among Different Cytoplasmic Male Sterility Lines and Their Maintainer Line in Soybean (Glycine max L.)

Plants, 2020
Cytoplasmic male sterility (CMS) lines and their maintainer line have the same nucleus but different cytoplasm types. We used three soybean (Glycine max L.) CMS lines, JLCMS9A, JLCMSZ9A, and JLCMSPI9A, and their maintainer line, JLCMS9B, to explore ...
Chunjing Lin, Bao Peng, Yongkuan Li, Pengnian Wang, Guolong Zhao, Xiaoyang Ding, Rong Li, Limei Zhao, Chunbao Zhang   +8 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Soy Notes Soy Notes, for the Kansas Soybean Farmer

, 2009
This internet resource contains Fall 2009 The Kansas Soybean Commission and the Kansas Soybean Association – two distinct organizations that work together for Kansas soybean farmers.
Kansas Soybean Commission
core   +1 more source

Nectar secretion of RN-type cytoplasmic male sterility three lines in soybean [Glycine max (L.) Merr.]

Journal of Integrative Agriculture, 2018
Significant progress has been achieved in the use of heterosis in soybean and several soybean hybrids have been released in China. However, broad use of hybrid soybean seed is limited due to low seed setting of female parents.
Jing-yong ZHANG, Huan SUN, Li-mei ZHAO, Chun-bao ZHANG, Hao YAN, Bao PENG, Wen-bin LI   +6 more
doaj   +1 more source