Results 71 to 80 of about 2,250,967 (273)

Abemaciclib: a CDK4/6 inhibitor for the treatment of HR+/HER2– advanced breast cancer

open access: yesDrug Design, Development and Therapy, 2018
Silvia Paola Corona,1 Daniele Generali2 1Radiation Oncology Department, Peter MacCallum Cancer Centre, Bentleigh East, VIC, Australia; 2Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy Abstract: Although early ...
Corona SP, Generali D
doaj  

Surfactant Protein D Binds to Coxiella burnetii and Results in a Decrease in Interactions with Murine Alveolar Macrophages. [PDF]

open access: yesPLoS ONE, 2015
Coxiella burnetii is a Gram-negative, obligate intracellular bacterium and the causative agent of Q fever. Infections are usually acquired after inhalation of contaminated particles, where C.
Kelly A Soltysiak   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Dysmicoccus de la Región Neotropical (Hemiptera: Pseudococcidae) Dysmicoccus from the Neotropical Region (Hemiptera: Pseudococcidae)

open access: yesRevista de la Sociedad Entomológica Argentina, 2009
Se describen e ilustran 16 especies: D. alius sp. nov., D. bonaerensis sp. nov., D. cacao sp. nov., D. caribensis sp. nov., D. fusagasugae sp. nov., D. gracilis sp. nov., D. patagonicus sp. nov., D. perotensis sp. nov., D. pini sp. nov., D.
María Cristina Granara de Willink
doaj  

Structural requirements for SP-D function in vitro and in vivo: therapeutic potential of recombinant SP-D.

open access: yesImmunobiology, 2003
Surfactant protein D has multiple functions in innate immunity in the lung. The generation of SP-D knock-out mice has revealed a central role for this protein in the control of lung inflammation. Accumulating evidence in mouse models of infection and inflammation indicates that truncated recombinant forms of surfactant protein D are biologically active
Clark, Howard, Reid, Kenneth B.M.
openaire   +2 more sources

Les Dactylogyridae (Plathelminthes, Monogenea) des Cyprinidae du genre Barbus du Sud Cameroun [PDF]

open access: yes, 1987
Nous décrivons sur cinq espèces de #Barbus$ (Téléostéens, Cyprinidae), du sud Cameroun, 14 espèces nouvelles de #Monogenea Dactylogyridae$. Ce sont : chez #B. jae : Dactylogyrus kii$ n. sp.; #D. jaei$ n. sp. et #Dactylogyroides biradius$ n. sp.; chez #B.
Birgi, E., Lambert, A.
core  

Integration with respect to the Haar measure on unitary, orthogonal and symplectic group

open access: yes, 2004
We revisit the work of the first named author and using simpler algebraic arguments we calculate integrals of polynomial functions with respect to the Haar measure on the unitary group U(d).
Collins, Benoit, Sniady, Piotr
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Dysmicoccus de la Región Neotropical (Hemiptera: Pseudococcidae)

open access: yesRevista de la Sociedad Entomológica Argentina, 2009
Se describen e ilustran 16 especies: D. alius sp. nov., D. bonaerensis sp. nov., D. cacao sp. nov., D. caribensis sp. nov., D. fusagasugae sp. nov., D. gracilis sp. nov., D. patagonicus sp. nov., D. perotensis sp. nov., D. pini sp. nov., D.
María Cristina GRANARA de WILLINK
doaj  

A monograph of Afrotropical and Mediterranean Derelomus Schoenherr, 1825 (Coleoptera: Curculionidae) with the descriptions of 14 new species

open access: yesEuropean Journal of Taxonomy
The species of the genus Derelomus Schoenherr, 1825 (Curculionidae: Curculioninae: Derelomini) from the Afrotropical (excluding Madagascar) and Mediterranean regions are here revised.
Julien M. Haran   +4 more
doaj   +1 more source

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