Results 141 to 150 of about 34,163 (302)

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

open access: yesAdvanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan   +7 more
wiley   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

open access: yesAdvanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo   +11 more
wiley   +1 more source

Multifunctional MIMO systems: A combined diversity and multiplexing design perspective

open access: yes, 2010
In this treatise we investigate the design alternatives of different multiple-input multiple-output schemes while considering the attainable diversity gains, multiplexing gains, and beamforming gains.
El Hajjar, Mohammed, Hanzo, Lajos
core  

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

Components that Enable Space Division Multiplexing

open access: yesAsia Communications and Photonics Conference 2014, 2014
The success of spatial multiplexing depends on highly integrated and cost effective devices and components. We compare the strengths and weaknesses of SDM components including silicon photonics, 3D waveguides, all-fiber mode-multiplexers, and bulk-optics wavelength selective switches and gain equalizers.
openaire   +2 more sources

Novel Optical Fibers for High-Capacity Transmission System

open access: yesDianxin kexue, 2014
Novel optical fibers for increasing capacity for transmission system was discussed.For conventional fibers for long haul transmission,because transmission impairments such as chromatic dispersion,polarization-mode dispersion can be perfectly compensated ...
Mingjun Li, Hao Chen
doaj   +2 more sources

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng   +7 more
wiley   +1 more source

Multicore EDFA for Space Division Multiplexing

open access: yesIEICE Transactions on Communications, 2013
TSUCHIDA, Yukihiro   +2 more
openaire   +2 more sources

Decision circuit and bit error rate estimation for absolute polar duty cycle division multiplexing

open access: yes, 2008
A novel concepts of decision circuit and Bit-error-rate (BER) estimation method for Absolute Polar Duty Cycle Division Multiplexing (AP-DCDM) is proposed The concepts have significant differences to those used in conventional microwave communication ...
Abas, A.F.   +6 more
core  

High efficient employment of hybrid space division multiplexing/time division multiplexing techniques in active/passive optical transparent networks

open access: yes
This paper has demonstrated the high efficient employment of space division multiplexing and time division multiplexing techniques. The high performance efciency of these networks are demonstrated based on the selection of routing algorithms in active/
Nallathambi, Golden Stepha   +8 more
core   +1 more source

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