Results 71 to 80 of about 1,043,123 (271)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

How to Host a Data Competition: Statistical Advice for Design and Analysis of a Data Competition

open access: yes, 2019
Data competitions rely on real-time leaderboards to rank competitor entries and stimulate algorithm improvement. While such competitions have become quite popular and prevalent, particularly in supervised learning formats, their implementations by the ...
Anderson-Cook, Christine M.   +5 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Modern approaches to designing of many-storeyed housing estates in conditions hot-arid climate (on an example of the UNITED ARAB EMIRATES)

open access: yesRUDN Journal of Engineering Research, 2012
In article modern problems of space-planning, constructive solutions of modern perspective multipurpose housing estates in the conditions of a hot arid climate, with emphasis on national features of the United Arab Emirates are considered.
N N Korshunova, Akhmed Ahmed Inshasi
doaj  

Primary and secondary school in Novokuznetsk

open access: yesПроект Байкал
The article considers the space-planning solution for the school building designed by AB PRO and the existing constraints, which influenced the formation process. The article features the tasks, which were faced by the author, and their solutions.
Валерий Цой   +2 more
doaj   +1 more source

Planning and Design of Open Public Space in the Coastal Zone [PDF]

open access: yesIgra Ustvarjalnosti, 2017
By changing the spatial planning policy after 1991, a new practice of spatial development planning was introduced for the Slovenian coastal zone as well. This framework also involves the planning and design of open public space in the narrow coastal zone.
Gregor Čok
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Space Trajectory Planning with a General Reinforcement-Learning Algorithm

open access: yesAerospace
Space trajectory planning is a complex combinatorial problem that requires selecting discrete sequences of celestial bodies while simultaneously optimizing continuous transfer parameters.
Andrea Forestieri, Lorenzo Casalino
doaj   +1 more source

Accessibility as a criterion of quality in an architectural spatial environment (on the example of the city of Almaty)

open access: yesBudownictwo o Zoptymalizowanym Potencjale Energetycznym, 2020
The main function of architecture is to arrange living space for everyone regardless of their citizenship, social status, age, and physical abilities.
Gulnara Abdrassilova   +1 more
doaj   +1 more source

METHODOLOGICAL APPROACH TO DETERMINING THE ORDER OF USE OF APARTMENTS WITH DIFFERENT SPACE-PLANNING SOLUTIONS

open access: yesCriminalistics and Forensics, 2020
The article examines the methodical approach to determining the right to use apartments, according to different space-planning solutions, in particular, in the conditions of the apartments that are designed and built for one family living. As well as in the conditions of the old buildings, which do not comply with current regulatory documents and rules.
openaire   +1 more source

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