Results 41 to 50 of about 13,348,458 (329)
Space Assurance or Space Dominance? The Case Against Weaponizing Space [PDF]
Argues that the pursuit of space dominance could impair global commerce, produce long-lasting, environmental debris in space, and harm alliance ties as well as relations between the United States and Russia and ...
Christopher Clary, Michael Krepon
core
Momentum space properties from coordinate space electron density
Electron density and electron momentum density, while independently tractable experimentally, bear no direct connection without going through the many-electron wave function.
Anjali Kshirsagar +4 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Beyond Ungoverned Spaces: Connecting the Dots between Relative Deprivation, Banditry, and Violence in Nigeria [PDF]
Promise Frank Ejiofor
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Orbital Space Environment and Space Situational Awareness Domain Ontology [PDF]
A short summary paper of my Orbital Space Domain Ontology project (purl.org/space-ontology), originally conceived in 2011. Since then I've sought (without success) opportunities to realize it (either as a PhD or other degree thesis; or in an employment ...
Rovetto, Robert J.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

