Results 101 to 110 of about 1,126,883 (314)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Spectrophotometric properties of Martian soil at the landing area of the Tianwen–1 Zhurong rover
Astronomy & AstrophysicsContext. The Navigation and Terrain Camera (NaTeCam) on board the Zhurong rover acquired extensive imaging data of the landing site under a wide range of phase angles, providing a unique opportunity to investigate the photometric properties of this area.
Zhou Xiang +7 more
doaj +1 more source
Space-Time Human Behaviour and Models of Locomotion: the Case of Students in the City of Volos, Greece [PDF]
The problem of space-time human behaviour is currently a very active subject of research in the geography and transport literature. The main objective of this study is the investigation of the factors that configure the dynamics of in-the-city individual
Fotini Moustou, Yorgos Photis
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
ACTIVITY SHAPES : Analysis methods of video-recorded human activity in a co-visible space
, 2012 The aim of this research is to develop two methods to help us understand the fundamental distinctionsamong human activities in terms of spatial occupancy.
Ellen, Y I L U E N D O +2 more
core
Sampling Chemical Space: Activity Cliffs, Extended Similarity, and ML Performance
The presence of Activity Cliffs (ACs) has been known to represent a challenge for QSAR modeling. With its data high dependency, Machine Learning QSAR models will be highly influenced by the activity landscape of the data.
Ramon, Miranda-Quintana +1 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The disrupted jet stream and its influence on flight time during solar proton events
Scientific ReportsThe long-chain effects of eruptive solar activities on Earth’s magnetosphere, ionosphere, and the mid-to-lower atmospheric circulation are an important theoretical research topic in the fields of space weather and atmospheric science.
Xiaoheng Xu +17 more
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Space WeatherSpace radiation poses a significant threat to the reliability of spacecraft equipment, while traditional static space environment models exhibit substantial inaccuracies in calculating on‐orbit error rates. This study investigates single‐event functional
Yingqi Ma +12 more
doaj +1 more source