Results 71 to 80 of about 11,957,490 (337)
Remote state preparation and teleportation in phase space
Continuous variable remote state preparation and teleportation are analyzed using Wigner functions in phase space. We suggest a remote squeezed state preparation scheme between two parties sharing an entangled twin beam, where homodyne detection on one ...
Andreoni A +15 more
core +1 more source
Constructing reparametrization invariant metrics on spaces of plane curves [PDF]
Metrics on shape space are used to describe deformations that take one shape to another, and to determine a distance between them. We study a family of metrics on the space of curves, that includes several recently proposed metrics, for which the metrics
Bauer +36 more
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Production Efficiency of Ultracold Feshbach Molecules in Bosonic and Fermionic Systems [PDF]
We investigate the production efficiency of ultracold molecules in bosonic $^{85}$Rb and fermionic $^{40}$K when the magnetic field is swept across a Feshbach resonance.
A. C. Wilson +8 more
core +4 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Efficiency of molecular machines with continuous phase space
We consider a molecular machine described as a Brownian particle diffusing in a tilted periodic potential. We evaluate the absorbed and released power of the machine as a function of the applied molecular and chemical forces, by using the fact that the ...
Golubeva, N., Imparato, A., Peliti, L.
core +1 more source
Space-Efficient Manifest Contracts [PDF]
The standard algorithm for higher-order contract checking can lead to unbounded space consumption and can destroy tail recursion, altering a program's asymptotic space complexity. While space efficiency for gradual types---contracts mediating untyped and typed code---is well studied, sound space efficiency for manifest contracts---contracts that check ...
openaire +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source

