Results 71 to 80 of about 11,957,490 (337)

Remote state preparation and teleportation in phase space

open access: yes, 2003
Continuous variable remote state preparation and teleportation are analyzed using Wigner functions in phase space. We suggest a remote squeezed state preparation scheme between two parties sharing an entangled twin beam, where homodyne detection on one ...
Andreoni A   +15 more
core   +1 more source

Constructing reparametrization invariant metrics on spaces of plane curves [PDF]

open access: yes, 2014
Metrics on shape space are used to describe deformations that take one shape to another, and to determine a distance between them. We study a family of metrics on the space of curves, that includes several recently proposed metrics, for which the metrics
Bauer   +36 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Production Efficiency of Ultracold Feshbach Molecules in Bosonic and Fermionic Systems [PDF]

open access: yes, 2004
We investigate the production efficiency of ultracold molecules in bosonic $^{85}$Rb and fermionic $^{40}$K when the magnetic field is swept across a Feshbach resonance.
A. C. Wilson   +8 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Efficiency of molecular machines with continuous phase space

open access: yes, 2012
We consider a molecular machine described as a Brownian particle diffusing in a tilted periodic potential. We evaluate the absorbed and released power of the machine as a function of the applied molecular and chemical forces, by using the fact that the ...
Golubeva, N., Imparato, A., Peliti, L.
core   +1 more source

Space-Efficient Manifest Contracts [PDF]

open access: yesACM SIGPLAN Notices, 2015
The standard algorithm for higher-order contract checking can lead to unbounded space consumption and can destroy tail recursion, altering a program's asymptotic space complexity. While space efficiency for gradual types---contracts mediating untyped and typed code---is well studied, sound space efficiency for manifest contracts---contracts that check ...
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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